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Rabbit Anti-ENDOGL1 Polyclonal Antibody#abs141119

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Description

Catalog-specification	Delivery time	USD price
abs141119-100ug	1-2 Weeks	301.0
abs141119-50ug	1-2 Weeks	201.0

Overview
catalog	abs141119
Other names	Endo G-like 1, also known as Endonuclease G-like 1 or ENDOGL 1, is an enzyme with exonuclease activity that operates in a 5' to 3' direction. It is structurally similar to endonuclease G and is localized in the mitochondria. Other aliases for this protein include ENDOGL2, Endonuclease G like 2, and Endonuclease G-like 1. It is also referred to as ENGL a, ENGL, ENGL B, ENGLA, and ENGLB. It is encoded by the MGC125944 and MGC125945 genes. Functionally, it acts as a nuclease, specifically in the mitochondria, under the name Nuclease EXOG or Nuclease EXOG mitochondrial.
Source	Rabbit
Specificity	The ENDOGL1 Antibody is designed to specifically detect and measure the total amount of ENDOGL1 protein present in an organism at its natural levels. This antibody allows researchers to study and analyze the endogenous levels of ENDOGL1, providing valuable insights into its functions and potential roles in various biological processes. By targeting the endogenous form of ENDOGL1, this antibody ensures accurate and reliable results, contributing to a better understanding of ENDOGL1's biological significance.
Species Reactivity	Human
Antigen	ENDOGL1
Application	For Western blot analysis, a dilution of 1:500 to 1:1000 is recommended. When performing immunofluorescence or immunocytochemistry, a dilution of 1:100 to 1:500 is suitable. For ELISA using peptides, a dilution of 1:20000 to 1:40000 is suggested. It is important to follow recommended dilution guidelines to obtain accurate and reliable results in your experiments.
Immunogen	A synthesized peptide.
MW	41 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography utilizing SulfoLink™ Coupling Resin was employed to purify the antiserum. A highly similar content can be created by rephrasing the original statement to maintain the same meaning, while using different words and sentence structure.
Clonality	Polyclonal Antibody
Stability & Storage	Make sure to store the item at -20 °C for a period of one year and prevent it from undergoing multiple freeze/thaw cycles.
Storage buffer	This is a description of Rabbit IgG in phosphate buffered saline at pH 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. The product should be stored at -20 °C and is stable for 12 months from the date of receipt.
Target
Background	Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity.
Tissue specificity	Ubiquitous.
Celluar localization	Mitochondrion;
UniPort	Q9Y2C4