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Rabbit Anti-Elmo1 Polyclonal Antibody#abs138059

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Description

Catalog-specification	Delivery time	USD price
abs138059-100ug	1-2 Weeks	301.0
abs138059-50ug	1-2 Weeks	201.0

Overview
catalog	abs138059
Other names	ELMO-1, also known as Ced 12 homolog 1 or Engulfment and cell motility protein 1, is a human protein that plays a crucial role in the process of engulfment and cell motility. Its genetic code is represented by various forms, including CED-12, Ced12 homolog, and KIAA0281. ELMO-1 is a significant player in the overall movement processes in the human body, and any malfunction can lead to various illnesses. Despite its importance, there is still much to uncover about this protein, making it a target for extensive research. The protein's structure and functions may be used to develop therapies for various health issues in the future. MGC126406 is one of the genes involved in the production of this protein, and it has been found to be active in different tissues and cell types in the body. In conclusion, ELMO-1 is an important protein whose study can lead to groundbreaking advancements in medicine.
Source	Rabbit
Specificity	The Elmo1 Antibody is capable of detecting the total amount of endogenous Elmo1 in the sample tested. This means that the antibody is able to bind to Elmo1 protein regardless of its conformational state, location or modification. By using this antibody, researchers can accurately determine the level of Elmo1 present in their samples, which is important in understanding its biological function and potential implications in disease.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Zebrafish;Chicken;Rabbit;Xenopus;Dog;Horse;Bovine;Sheep;Pig
Antigen	Elmo1
Application	The recommended dilution for Western blotting is between 1:1000 to 1:3000, while for IF/ICC, a dilution of 1:100 to 1:500 is recommended. For ELISA with peptide, a dilution range of 1:20000 to 1:40000 is suggested. It is important to note that these dilution ranges may vary depending on the specific experimental conditions and reagents being used.
Immunogen	A synthesized peptide derived from human Elmo1.
MW	83 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized in the purification process of the antiserum through peptide affinity chromatography. Let's generate a similar content by rearranging the provided information while maintaining its original context.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the integrity of the product, it is advisable to keep it in a cold environment of -20 °C for a duration of one year. It is important to note that exposing the product to repeated freeze/thaw cycles can greatly compromise its quality. Thus, it is advisable to handle the product with care to ensure its longevity.
Storage buffer	The recommended storage condition for Rabbit IgG is -20 °C in a solution containing phosphate buffered saline (pH 7.4), 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This formulation ensures stability for a period of 12 months starting from the date of receipt. It is important to note that the generated content above is a rearrangement of the original information, with emphasis on maintaining its essence.
Target
Background	Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Tissue specificity	Widely expressed, with a higher expression in the spleen and placenta.
Posttranslational modification	Phosphorylated by HCK.
Celluar localization	Cytosol;Plasma Membrane;
UniPort	Q92556