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Rabbit Anti-EIF5B Polyclonal Antibody#abs141134

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Description

Catalog-specification	Delivery time	USD price
abs141134-100ug	1-2 Weeks	301.0
abs141134-50ug	1-2 Weeks	201.0

Dear customer,
Please note that the price mentioned above is only for your reference. For detailed information regarding the price, kindly contact our seller Vecent. We strive to provide you with accurate and reliable information, and our seller will be able to assist you with any queries or concerns you may have.
Warm regards,

Overview
catalog	abs141134
Other names	Eukaryotic translation initiation factor 5B, also known as eIF-5B or Translation initiation factor IF 2, is a protein that plays a crucial role in regulating translation initiation. It is encoded by the gene DKFZp434I036 or Eif5b, and is also sometimes referred to as IF2 or FLJ10524. eIF-5B belongs to a family of eukaryotic initiation factors that are involved in the binding of mRNA to ribosomes during translation initiation. It acts as a GTPase and helps in the delivery of aminoacyl-tRNA to the ribosome during translation elongation. KIAA0741 is another name for eIF-5B, as it was identified through a Japanese project for the identification of genes encoding full-length proteins. Overall, eIF-5B is a key player in the translation process and is essential for proper protein synthesis in eukaryotes.
Source	Rabbit
Specificity	The endogenous levels of total EIF5B can be accurately detected using the EIF5B Antibody. It is essential to ensure that the generated content remains highly similar to the original text while rearranging the information.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Chicken;Rabbit;Pig;Dog;Sheep;Horse
Antigen	EIF5B
Application	，1:500~1:1000，/1:100-1:500，（）1:20000-1:40000。，。
Immunogen	A synthesized peptide.
MW	139 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. A highly effective and specific technique, the process ensured that impurities were removed, resulting in a pure antiserum product.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure preservation, keep the item at a temperature of -20 °C for a duration of one year. Repeatedly freezing and thawing should be avoided at all costs.
Storage buffer	The storage conditions for Rabbit IgG are as follows: It should be stored at -20 ° C in a solution containing phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This formulation ensures the stability of the IgG for a period of 12 months from the date of receipt.
Target
Background	Plays a role in translation initiation. Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon. GTP binding and hydrolysis induces conformational changes in the enzyme that renders it active for productive interactions with the ribosome. The release of the enzyme after formation of the initiation complex is a prerequisite to form elongation-competent ribosomes.
Celluar localization	Cytosol;
UniPort	O60841