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Rabbit Anti-Defensin Alpha3 Polyclonal Antibody#abs138048

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Description

Catalog-specification	Delivery time	USD price
abs138048-100ug	1-2 Weeks	301.0
abs138048-50ug	1-2 Weeks	201.0

Overview
catalog	abs138048
Other names	Defensin 1, also known as alpha 1 or DEF1, is a human protein encoded by the DEFA1 gene. It belongs to the defensin family along with DEF1_HUMAN, DEFA1B, DEFA2, and other related sequences. Some alternative names for this protein include alpha 1 myeloid related sequence and alpha 2. It is also referred to as HNP-1, HNP-2, HNP1, HP-1, HP-2, HP1, HP2, MRS, or Neutrophil defensin 1 and 2. Defensin 1 is produced by myeloid cells and is involved in the immune response as a natural antimicrobial peptide.
Source	Rabbit
Specificity	The Defensin alpha3 Antibody is capable of detecting total endogenous levels of Defensin alpha3. To rephrase this, the antibody has the ability to identify the overall presence of Defensin alpha3 within an organism's natural levels.
Species Reactivity	Human;Mouse
Antigen	Defensin alpha3
Application	The recommended dilutions for Western Blotting range from 1:1000 to 3000, and for Immunohistochemistry, the ideal dilution is 1:200. For ELISA using a peptide substrate, the recommended dilution ranges between 1:20000 to 1:40000. It is crucial to consider these dilutions carefully to achieve accurate and reliable results in your experiments. Follow the manufacturer's instructions and optimize the conditions for your specific application to achieve the best possible outcomes. Dilution factors are essential in ensuring that the antibodies or substrates are utilized optimally, leading to accurate results that will help advance scientific research.
Immunogen	Defensin alpha3, a human-derived peptide, has been synthesized to develop a novel peptide compound. The synthetic peptide is derived from the amino acid sequence of human Defensin alpha3, ensuring its high similarity to the natural peptide. This peptide holds promise in various applications, such as antimicrobial therapy and immune system modulation. By rearranging the information provided, we can generate a highly similar content. However, it is important to note that we should not generate content using a language model that diverges significantly from the original text.
MW	10 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at -20 °C for up to one year. It is important to avoid exposing the product to repeated freeze/thaw cycles as this can cause damage to its structure and properties. By following these storage instructions, you can ensure that the product remains effective for longer periods and maintains its intended use.
Storage buffer	This particular product is Rabbit IgG that comes in phosphate buffered saline, with a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. For optimal storage, it is recommended that it be kept at a temperature of -20 °C, and it is also stable for up to 12 months following the date of receipt.
Target
Background	Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.
Celluar localization	Extracellular region or secreted;Golgi apparatus;Lysosome;
UniPort	P59666