Rabbit Anti-CPN2 Polyclonal Antibody#abs140980

Rabbit Anti-CPN2 Polyclonal Antibody#abs140980

Please note that the price provided is only for reference purposes. For detailed pricing information, please kindly get in touch with our seller, Vecent. The pricing may vary based on different factors, and our team is more than happy to assist you with any questions or concerns you may have. We...

Description

Catalog-specificationDelivery timeUSD price

abs140980-100ug

1-2 Weeks

301.0

abs140980-50ug

1-2 Weeks

201.0

Please note that the price provided is only for reference purposes. For detailed pricing information, please kindly get in touch with our seller, Vecent. The pricing may vary based on different factors, and our team is more than happy to assist you with any questions or concerns you may have. We look forward to hearing from you soon.


Overview

catalog

abs140980
Other namesThis gene encodes the 83 kDa chain of carboxypeptidase N, a large subunit of the enzyme that cleaves the C-terminal amino acid from peptide substrates. It is also known as carboxypeptidase N polypeptide 2 and is a regulatory subunit of the enzyme. Carboxypeptidase N subunit 2 is synthesized as a precursor and undergoes proteolytic cleavage to generate the mature subunit. It is involved in many important biological processes in the body, including protein metabolism and blood coagulation. As a result, mutations in this gene have been linked to a number of human diseases.
SourceRabbit
SpecificityThe total CPN2 levels can be detected using the CPN2 Antibody, which specifically targets the endogenous CPN2 protein.
Species ReactivityHuman
AntigenCPN2
ApplicationFor Western Blot, the recommended dilutions are 1:500 to 1:1000 while for Immunofluorescence or Immunocytochemistry, the suggested dilutions range from 1:100 to 1:500. When conducting ELISA using peptide, the optimal dilutions to use are between 1:20000 and 1:40000. It's important to note that these dilutions should be optimized for each individual experiment.
ImmunogenA synthesized peptide.
MW61 KD
Properties

Concentration

1mg/ml

purificationThe purification of the antiserum involved the use of SulfoLink™ Coupling Resin in peptide affinity chromatography. This process was employed to ensure the purity of the final product.
ClonalityPolyclonal Antibody
Stability & StorageTo ensure optimal storage, it is advised that this item be kept at a temperature of -20°C for a period of one year. Please take care to prevent repeated cycles of freezing and thawing, as this may negatively impact the item's longevity and quality. It is recommended to follow these guidelines closely in order to maintain the integrity of the item.
Storage bufferPhosphate buffered saline with Rabbit IgG is a well-preserved solution with a pH of 7.4. It contains 150mM of NaCl, 0.02% sodium azide, and is supplemented with 50% glycerol. For optimal stability, it should be stored at -20 °C. This formulation ensures the longevity of the product, allowing it to remain stable for 12 months from the date of receipt.

Target

Background

The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit.

Posttranslational modificationWhether or not any Cys residues participate in intrachain bonds is unknown, but they do not form interchain disulfide bonds with the 50 kDa catalytic subunit.
Celluar localizationExtracellular region or secreted;
UniPortP22792


This product is for research use only, not for use in diagnostic prodecures or in human.


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