Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-CDK10 Polyclonal Antibody#abs133587

Please note that the price mentioned above is for your reference only. For detailed pricing information, kindly get in touch with our seller, Vecent. We encourage you to contact Vecent to obtain accurate and up-to-date pricing details. Western blot analysis of extracts from 293 cells, using...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs133587-100ug	1-2 Weeks	301.0
abs133587-50ug	1-2 Weeks	201.0

Overview
catalog	abs133587
Other names	Cyclin-dependent kinase 10 (CDK10) is a member of the CDC2 related protein kinase family, also known as PISSLRE. CDK10 is a serine/threonine protein kinase that plays an essential role in regulating the cell division process. It is responsible for controlling the progression of cells from the G1 phase to the S phase in the cell cycle. CDK10 is closely related to other cyclin-dependent kinases and is involved in the regulation of various physiological processes, including transcription, RNA processing, and DNA damage repair. The protein kinase has been implicated in the development of several diseases, such as cancer, due to its role in cell proliferation. The identification of CDK10 has led to a deeper understanding of the molecular mechanisms that govern cell cycle regulation and has opened up new avenues for the development of therapies that target CDK10 in disease states.
Source	Rabbit
Specificity	The detected levels of total CDK10 protein are effectively recognized by the CDK10 Antibody.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Zebrafish;Chicken;Pig;Dog;Horse;Bovine;Sheep;
Antigen	CDK10
Application	1:500~1:1000 is the dilution for Western Blot (WB), while 1:100-1:500 is the dilution for Immunofluorescence (IF) or Immunocytochemistry (ICC). For ELISA using peptides, the recommended dilution is 1:20000-1:40000. These dilutions are essential for accurate and precise detection of the target molecule in these assays. It is important to follow the recommended dilutions to obtain reliable and reproducible results in your experiments.
Immunogen	A synthesized peptide.
MW	43 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was purified through peptide affinity chromatography. It was a meticulous process that resulted in a highly purified antiserum free from impurities. The purity of the antiserum was achieved through the resin's capability to specifically bind to the peptide of interest, allowing for selective separation of the desired components. Overall, the use of peptide affinity chromatography and SulfoLink™ Coupling Resin proved to be an effective method for purifying the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal preservation, it is recommended that the item be stored at a temperature of -20 °C for a period of one year. To avoid compromising the item's quality, it is important to take precautions and refrain from exposing it to repeated cycles of freezing and thawing.
Storage buffer	The Rabbit IgG is preserved in a solution containing phosphate buffered saline with a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. To ensure its stability, it should be stored at -20 °C. This product is guaranteed to remain stable for a period of 12 months starting from the date of receipt.
Target
Background	Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells).
Celluar localization	Nucleus;
UniPort	Q15131