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Rabbit Anti-CD300LB Polyclonal Antibody#abs139677

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Description

Catalog-specification	Delivery time	USD price
abs139677-100ug	1-2 Weeks	301.0
abs139677-50ug	1-2 Weeks	201.0

Overview
catalog	abs139677
Other names	The CD300 antigen-like family member B, also known as CD300b, belongs to the CD300 molecule-like family. Some of its other aliases include CMRF35 A2, CMRF35-like molecule 7, CLM7, CLM7_HUMAN, Immune receptor expressed on myeloid cells 3, IREM 3, Leukocyte mono-Ig-like receptor 5, LMIR5, TREM 5, TREM5, and UNQ2530/PRO6029. This protein serves as a triggering receptor expressed on myeloid cells 5 and plays a vital role in regulating the immune response. Its functions include activating and inhibiting natural killer (NK) cells, as well as affecting dendritic cells and macrophages. Overall, CD300b is a highly versatile molecule involved in various aspects of the immune system.
Source	Rabbit
Specificity	Endogenous levels of total CD300LB can be accurately detected using the CD300LB antibody. A highly similar content could be generated by rearranging the original text information as follows: The CD300LB antibody is capable of detecting the endogenous levels of total CD300LB with precision.
Species Reactivity	Human
Antigen	CD300LB
Application	IHC 1:200, WB 1:1000-3000, and ELISA (peptide) 1:20000-1:40000 are the recommended dilutions for conducting these specific laboratory techniques.
Immunogen	A synthesized peptide derived from human CD300LB.
MW	23 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. To ensure a high level of similarity, the content has been rearranged while still accurately conveying the information provided in the original text.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a duration of one year. It's important to avoid subjecting the product to freeze and thaw cycles, as these can have a detrimental effect.
Storage buffer	The provided content is about the storage and stability information of Rabbit IgG. Here's a rearranged version: To ensure the stability of Rabbit IgG, it is suspended in phosphate-buffered saline with a pH of 7.4. The solution also contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20°C. This product has a shelf life of 12 months from the date of receipt.
Target
Background	Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.
Tissue specificity	Expressed exclusively in myeloid lineages.
Posttranslational modification	Phosphorylation on Tyr-188 by FYN is required for interaction with GRB2.
Celluar localization	Plasma Membrane;
UniPort	A8K4G0