Rabbit Anti-TAF15 Polyclonal Antibody#abs132803

Rabbit Anti-TAF15 Polyclonal Antibody#abs132803

Please note that the price mentioned above is only for your reference. For detailed pricing information, we suggest you get in touch with our seller, Vecent. Western blot analysis of TAF15 expression in Hela cell lysate,The lane on the left is treated with the antigen-specific peptide. This...

Description


Catalog-specificationDelivery timeUSD price

abs132803-50ug

1-2 Weeks

201.0

abs132803-100ug

1-2 Weeks

301.0

Please note that the price mentioned above is only for your reference. For detailed pricing information, we suggest you get in touch with our seller, Vecent.


Overview

catalog

abs132803
Other namesThe 68 kDa TATA-binding protein-associated factor goes by many names, including Npl3, RBP56, RBP56_HUMAN, and TAF. This RNA-binding protein 56, also known as TAF15, is essential in the binding of TATA-box binding protein (TBP) to RNA polymerase II. TAF15 also has a crucial role in regulating gene expression. Additionally, this protein is involved in various cellular processes, such as transcriptional regulation, mRNA processing, and RNA transport. TAF15 is sometimes referred to as TAF(II)68, TAF2N, or TATA-binding protein-associated factor 2N, but regardless of the name, it is a vital component in RNA function within cells.
SourceRabbit
SpecificityThe total TAF15 levels can be detected by the TAF15 antibody, which specifically targets the endogenous form of TAF15 protein.
Species ReactivityHuman;Mouse
AntigenTAF15
ApplicationWB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
ImmunogenA synthesized peptide.
MW62 kDa
Properties

Concentration

1mg/ml

purificationUsing SulfoLink™ Coupling Resin, the purification of the antiserum was performed through peptide affinity chromatography.
ClonalityPolyclonal Antibody
Stability & StorageTo ensure proper storage, keep the product at a temperature of minus 20 degrees Celsius for an entire year. It is important to avoid any instances of freezing and thawing cycles that may occur. This will help to maintain the integrity and effectiveness of the product over time.
Storage bufferIn a solution of phosphate buffered saline with a pH of 7.4 and 150mM NaCl, Rabbit IgG is present with 0.02% sodium azide and 50% glycerol.

Target

Background

RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II).

Tissue specificityUbiquitous. Observed in all fetal and adult tissues.
Posttranslational modificationDimethylated by PRMT1 at Arg-206 to asymmetric dimethylarginine. The methylation may favor nuclear localization and positive regulation of TAF15 transcriptional activity.ADP-ribosylated during genotoxic stress.
Celluar localizationNucleus;
UniPortQ92804


Western blot analysis of TAF15 expression in Hela cell lysate,The lane on the left is treated with the antigen-specific peptide.

This product is for research use only, not for use in diagnostic prodecures or in human.


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