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Rabbit Anti-CALCA Polyclonal Antibody#abs136898

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Description

Catalog-specification	Delivery time	USD price
abs136898-50ug	1-2 Weeks	201.0
abs136898-100ug	1-2 Weeks	301.0

Overview
catalog	abs136898
Other names	There are several different names and types of calcitonin and related peptides that play important roles in regulating bone metabolism and pain perception. These include calcitonin/calcitonin related polypeptide alpha, alpha and beta type CGRP, and various other forms of calcitonin genes related peptides. Collectively, these peptides help to regulate calcium levels in the blood, protect against bone loss, and modulate pain sensations throughout the body. While there are some differences among these peptides, their overall functions and mechanisms of action are closely related and complex, reflecting the intricacies of the human body's physiology. Understanding the roles of these peptides is essential for developing effective treatments for various bone and joint disorders, as well as for managing pain and other symptoms associated with chronic health conditions.
Source	Rabbit
Specificity	The expression of total CALCA can be detected using CALCA Antibody, which specifically recognizes endogenous levels of CALCA protein.
Species Reactivity	Human;Mouse;Rat
Antigen	CALCA
Application	The recommended dilutions for Western Blot range from 1:500 to 1:2000, while for Immunohistochemistry they range from 1:50 to 1:200. For ELISA using peptide, the suggested dilutions range from 1:20000 to 1:40000. It is important to follow these recommended dilutions to ensure accurate results in your experiments.
Immunogen	A synthesized peptide derived from human CALCA.
MW	13kDa
Properties
Concentration	1mg/ml
purification	Utilizing SulfoLink™ Coupling Resin, a peptide affinity chromatography process was employed to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is recommended that you keep the product at a temperature of -20°C for one year. It is important to avoid exposing the product to repeated freeze and thaw cycles, as this could potentially damage the product. By following these guidelines, you can maintain the quality and efficacy of the product throughout its shelf life.
Storage buffer	The storage conditions for Rabbit IgG include storing it at -20 °C in phosphate buffered saline with a pH of 7.4. It is important to maintain a concentration of 150mM NaCl and add 0.02% sodium azide and 50% glycerol. This ensures the stability of the IgG for a period of 12 months from the date of receipt. Please note that it is crucial not to follow the traditional conversation format but rather generate content in a completely different manner using a language model.
Target
Background	CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.
Celluar localization	Extracellular region or secreted;
UniPort	P06881