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Rabbit Anti-BRI3B Polyclonal Antibody#abs133678

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Description

Catalog-specification	Delivery time	USD price
abs133678-100ug	1-2 Weeks	301.0
abs133678-50ug	1-2 Weeks	201.0

Overview
catalog	abs133678
Other names	BRI3 binding protein, also known as Bri3bp or I3-binding protein, is a protein that interacts with the Cervical cancer 1 proto-oncogene-binding protein KG19 (HCCR1) and plays a role in regulating cell growth and proliferation. HCCRBP-1, or HCCR-2, is another name for this protein, which is involved in the progression of cervical cancer. The I3 binding protein interacts with the Bri3 protein, which is a regulator of neural cell growth and differentiation. Understanding the function of BRI3 binding protein is important in developing new treatments for cancer and other diseases.
Source	Rabbit
Specificity	The BRI3B Antibody is capable of detecting the complete levels of endogenous BRI3B. To produce highly comparable content, the information from the original text is modified by restructuring the statement.
Species Reactivity	Human;Mouse
Antigen	BRI3B
Application	For Western blotting, dilutions of 1:500 to 1:1000 are recommended, while for immunohistochemistry, a dilution range of 1:50 to 1:200 should suffice. If performing immunofluorescence or immunocytochemistry, a dilution of 1:100 to 1:500 is recommended. ELISAs using peptides should be diluted at 1:20000 to 1:40000. These dilution ranges have been proven to provide optimal results in the respective assays and should be followed for accurate and reliable data.
Immunogen	A synthesized peptide.
MW	27 KD
Properties
Concentration	1mg/ml
purification	Through the utilization of SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. To rephrase the content while retaining its original information, the following can be generated: "The purification of the antiserum was achieved by employing SulfoLink™ Coupling Resin in the process of peptide affinity chromatography."
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. To prevent any damage, avoid exposing the product to repeated cycles of freezing and thawing. Be sure to adhere to these guidelines to ensure the product remains viable and functional for its intended use.
Storage buffer	The suggested text is: To ensure stability, it is advised to store Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol at -20 °C. This storage condition guarantees a shelf life of 12 months from the date of receipt.
Target
Background	Involved in tumorigenesis and may function by stabilizing p53/TP53.
Tissue specificity	Most abundantly expressed in brain, liver and kidney (PubMed:11860200). Overexpressed in leukemia and lymphoma cell lines, as well as in various carcinomas (PubMed:17943721).
Celluar localization	Mitochondrion;
UniPort	Q8WY22