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Rabbit Anti-BMP4 Polyclonal Antibody#abs131261

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Description

Catalog-specification	Delivery time	USD price
abs131261-50ug	1-2 Weeks	201.0
abs131261-100ug	1-2 Weeks	301.0

Overview
catalog	abs131261
Description	These molecules have the ability to stimulate the formation of cartilage and bones, as well as play a role in various developmental processes such as mesoderm induction, tooth development, limb formation and fracture repair. Additionally, they work together with PTHLH/PTHRP to promote the growth of ducts during embryonic mammary development and inhibit hair follicle induction.
Other names	One possible rearrangement of the original text is: BMP-2B, also known as bone morphogenetic protein 2B, and BMP-4, also known as bone morphogenetic protein 4, are important signaling molecules involved in the regulation of bone and cartilage development. BMP2B1 and BMP4 belong to the larger BMP family and are highly conserved across species. BMP4_HUMAN, OFC11, and MCOPS6 are all alternative names for BMP-4. Another rearrangement could be: As part of the BMP family, BMP-2B and BMP-4 play crucial roles in the development of bone and cartilage tissues. They are also known by alternative names such as BMP2B1, BMP4_HUMAN, zbmp-4, and DVR4. BMP4_HUMAN, OFC11, and MCOPS6 are human-specific names for BMP-4. Despite their different names, BMP2B and BMP4 share many similarities and are important targets for medical research.
Source	Rabbit
Specificity	The BMP4 Antibody has the ability to identify total BMP4 at its natural levels within the body. To create new content that is closely related to this statement, one could say that the BMP4 Antibody is capable of detecting total BMP4 that is present in the body's natural state.
Species Reactivity	Human;Mouse;Rat
Antigen	BMP4
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human BMP4.
MW	46 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography for purification.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the quality of the product, it is recommended to store it in a temperature-controlled environment with a temperature of -20 °C for up to one year. It's essential to avoid subjecting the product to frequent cycles of freezing and thawing, as this may compromise its integrity. By following these storage recommendations, you can guarantee the product's efficacy and stability.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity).
Tissue specificity	Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.
Celluar localization	Endoplasmic reticulum;Extracellular region or secreted;
UniPort	P12644

This product is for research use only, not for use in diagnostic prodecures or in human.

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