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Rabbit Anti-BMP2K Polyclonal Antibody#abs138398

Please note that the price mentioned above is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. Western blot analysis BMP2K using Jurkat whole cell lysates This product is for research use only, not for use in diagnostic...

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Description

Catalog-specification	Delivery time	USD price
abs138398-100ug	1-2 Weeks	301.0
abs138398-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.

Overview
catalog	abs138398
Other names	Bike kinase, also known as BMP 2 inducible protein kinase or BMP2K, is a protein involved in various cellular processes. It is encoded by the BMP2K gene and has been identified as a signaling molecule in the BMP-2 pathway. This kinase is responsible for the phosphorylation of target proteins, which ultimately leads to the activation of downstream signaling cascades. The expression of Bike kinase can be induced by BMP 2, a member of the bone morphogenetic protein family. Upon activation, Bike kinase plays a crucial role in mediating the effects of BMP 2 on cell proliferation, differentiation, and apoptosis. It is believed to regulate the development and maintenance of various tissues and organs. The exact mechanism of action of Bike kinase is still not fully understood. However, studies have shown that it interacts with other signaling molecules and forms complexes with them to activate specific downstream pathways. It has been implicated in the regulation of gene expression, cell cycle progression, and cell survival. In addition to its role in BMP 2 signaling, Bike kinase has also been associated with other cellular processes. It has been shown to be involved in DNA damage response, cell migration, and neuronal development. Furthermore, alterations in the expression of Bike kinase have been observed in various diseases, including cancer and neurodegenerative disorders. In summary, Bike kinase is a multifunctional protein that plays a critical role in BMP 2 signaling and other cellular processes. Its activation and regulation are tightly controlled and essential for proper cellular function. Further research is needed to fully understand the complex functions and molecular mechanisms of Bike kinase.
Source	Rabbit
Specificity	The BMP2K Antibody has the ability to identify the total BMP2K levels present in the body. This antibody is specially designed to detect endogenous levels of BMP2K protein. For accurate results, it is important to use this antibody at its recommended concentration. By using this antibody, researchers can better understand the role of BMP2K in various biological processes.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Rabbit;Pig;Dog
Antigen	BMP2K
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human BMP2K.
MW	129 kDa
Properties
Concentration	1mg/ml
purification	We utilized SulfoLink™ Coupling Resin in the peptide affinity chromatography process to purify the antiserum. Please rearrange the content to ensure high similarity while preserving the original text information.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure maximum effectiveness, it is recommended that the product be stored at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles, as this may compromise its quality and efficacy. So, it is advisable to take necessary precautions to maintain the product's stability and performance by following these storage guidelines.
Storage buffer	The recommended storage conditions for Rabbit IgG are at -20 °C in phosphate buffered saline, with a pH of 7.4. The solution should also contain 150mM NaCl and 0.02% sodium azide, which acts as a preservative. Additionally, it is advised to include 50% glycerol to maintain the stability of the IgG. This product is stable for a period of 12 months from the date of receipt.
Target
Background	May be involved in osteoblast differentiation.
Posttranslational modification	Autophosphorylated.
Celluar localization	Nucleus;
UniPort	Q9NSY1