Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-BAM32 Polyclonal Antibody#abs140377

Please note that the price provided above is only for your reference. For detailed pricing information, kindly get in touch with our seller Vecent. To create a unique version of the content, I will generate text in a distinctly different manner from the one generated by ChapGPT. Western blot...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs140377-100ug	1-2 Weeks	301.0
abs140377-50ug	1-2 Weeks	201.0

Overview
catalog	abs140377
Other names	The B cell adapter molecule of 32 kDa, also known as BAM32 or B lymphocyte adapter protein, is a protein involved in signaling pathways in B cells. It is encoded by the DAPP1 gene and is also referred to as DAPP1_HUMAN or DKFZp667E0716. BAM32 is a dual adaptor for phosphotyrosine and 3-phosphoinositides, playing a key role in the regulation of cellular processes such as proliferation, differentiation, and apoptosis. Despite its small size, this adapter molecule is crucial to the function of B cells and the immune system as a whole.
Source	Rabbit
Specificity	The BAM32 Antibody is able to detect the overall levels of endogenous BAM32 present in the system. The content can be rephrased by using synonymous words and rearranging the sentence structure to convey that the antibody can effectively detect the total BAM32 present.
Species Reactivity	Human;Mouse
Antigen	BAM32
Application	For Western blotting, the optimal dilution is 1:1000. When performing immunofluorescence/immunocytochemistry assays, a dilution range of 1:100-1:500 is recommended. For ELISA using peptide as the antigen, a dilution range of 1:20000-1:40000 is recommended for best results. It is important to maximize the sensitivity and specificity of your assays by using the appropriate dilutions for each application.
Immunogen	A synthesized peptide derived from human BAM32.
MW	32kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was purified through peptide affinity chromatography. To ensure the efficient elimination of impurities, this process was chosen as the optimal purification method.
Clonality	Polyclonal Antibody
Stability & Storage	Make sure to store at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the item to repeated freeze/thaw cycles.
Storage buffer	The rabbit IgG is suspended in phosphate buffered saline, pH 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20 °C and will remain stable for a period of 12 months from the date of receipt.
Target
Background	May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.
Tissue specificity	Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.
Posttranslational modification	Phosphorylated on tyrosine residues.
Celluar localization	Cytosol;Plasma Membrane;
UniPort	Q9UN19