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Rabbit Anti-AMPD3 Polyclonal Antibody#abs138720

Description

Catalog-specification	Delivery time	USD price
abs138720-100ug	1-2 Weeks	301.0
abs138720-50ug	1-2 Weeks	201.0

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Overview
catalog	abs138720
Other names	Adenosine monophosphate deaminase (AMPD) is an enzyme that plays a crucial role in purine nucleotide metabolism. There are different isoforms of AMPD, including isoform E or AMPD3. This isoform is also known as erythrocyte AMP deaminase or erythrocyte-specific protein since it is mostly found in red blood cells. AMPD3 catalyzes the conversion of adenosine monophosphate (AMP) to inosine monophosphate (IMP) by removing an amino group from AMP. This reaction is important for the recycling of purine nucleotides and the regulation of energy metabolism in erythrocytes and skeletal muscles. AMPD3 deficiency has been linked to various diseases, including nonspherocytic hemolytic anemia and myopathy. Therefore, understanding the function and regulation of AMPD3 can provide insights into the pathophysiology and potential therapeutic targets for these disorders.
Source	Rabbit
Specificity	The total AMPD3 levels can be detected using the AMPD3 Antibody, which specifically recognizes the endogenous levels of AMPD3.
Species Reactivity	Human;Mouse;Rat
Antigen	AMPD3
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human AMPD3.
MW	89 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain optimal conditions, it's recommended to store the product at a temperature of -20 °C for a duration of one year. It is important to avoid subjecting the product to repeated cycles of freezing and thawing.
Storage buffer	The recommended storage conditions for Rabbit IgG are as follows: -20 °C in phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This formulation ensures stability for a period of 12 months from the date of receipt. Please note that it is essential to adhere to these storage guidelines for optimal preservation of the product.
Target
Background	AMP deaminase plays a critical role in energy metabolism.
Celluar localization	Cytosol;Extracellular region or secreted;
UniPort	Q01432