Rabbit Anti-ALPK2 Polyclonal Antibody #abs130497

abs130497-50ug

1-2 Weeks

201

abs130497-100ug

1-2 Weeks

301

Description

ALPK2 is a member of the protein kinase superfamily that recognizes phosphorylation sites surrounded by peptides with an alpha-helical conformation. It belongs to the alpha-type protein kinase family and has two isoforms due to alternative splicing in humans. Its unique ability to recognize alpha-helical peptides sets it apart from other kinases and makes it a valuable player in intracellular signaling pathways.

Other names

Heart alpha-protein kinase, also known as ALPK2, is a protein in humans that is encoded by the FLJ34875 gene. It has also been referred to as Gm549 and HAK. Another gene associated with ALPK2 is FLJ43253. RGD1564431 is a related entry in the Rat Genome Database. This protein is involved in various cellular processes and plays an important role in cardiovascular health. By rearranging the original text, we have generated a new content that still conveys the same information.

Source

Rabbit

Specificity

ALPK2 Antibody detects endogenous levels of ALPK2.

Species Reactivity

Human;Rat

Application

ELISA (peptide) 1:20000-1:40000, IHC 1:50-1:200, and WB 1:500-1:2000 are the recommended dilution ranges for these assay techniques. ELISA with peptide antigens has the highest dilution range, followed by IHC, and WB has the lowest dilution range. It is important to use the appropriate dilution ratio to ensure accurate and reliable results. Please note that these dilution ranges may vary depending on the specific antibody and experimental conditions.

Immunogen

A synthesized peptide derived from human ALPK2.

Properties

Concentration

1mg/ml

Purification

The SulfoLink™ Coupling Resin was utilized for the peptide affinity chromatography purification of the antiserum. This resulted in the generation of a high-quality and purified antiserum product.

Clonality

Polyclonal Antibody

Stability & Storage

To preserve the integrity of the product, it is recommended to store it at a temperature of -20°C for a period of one year. It is important to avoid subjecting the product to repeated freeze and thaw cycles, as this may compromise its quality. Therefore, it is advisable to use appropriate storage conditions to ensure the product remains in top condition for its intended purpose.

Storage buffer

To store Rabbit IgG, use a solution of phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. Keep it at -20 °C for optimal storage conditions. This product will remain stable for up to 12 months from the date of receipt. Please ensure that you follow these instructions carefully to ensure the integrity of your Rabbit IgG.

Target

Background

A specific type of kinase is capable of detecting phosphorylation sites only if they are surrounded by peptides that adopt an alpha-helical conformation. This particular kinase shows a preference for alpha-helical structures and is therefore able to identify a specific pattern of peptides that are associated with this type of structural motif. The recognition of phosphorylation sites in this manner is crucial for many biological processes and this kinase plays an important role in modulating these pathways.

UniPort

Q86TB3