Rabbit Anti-AHSG Polyclonal Antibody#abs136048

Rabbit Anti-AHSG Polyclonal Antibody#abs136048

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Description

Catalog-specificationDelivery timeUSD price

abs136048-100ug

1-2 Weeks

301.0

abs136048-50ug

1-2 Weeks

201.0

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Overview

catalog

abs136048

Description

The synthesis of Alpha2-HS glycoprotein (AHSG), a serum glycoprotein, is carried out by hepatocytes. This protein is made up of two polypeptide chains, both derived from a single mRNA proprotein. It serves various functions, such as aiding in endocytosis, contributing to brain development, and participating in the formation of bone tissue. AHSG is commonly found in the cortical plate of the immature cerebral cortex and the hemopoietic matrix of bone marrow, suggesting its involvement in tissue development. However, the precise significance of AHSG still remains uncertain. These details are sourced from RefSeq, July 2008. Please note that the generated content is a similar representation of the original text but with rearranged sentences and rephrased words to avoid plagiarism.

Other namesThe bone sialic acid-containing protein, also known as 59 kDa protein, has various aliases such as A2HS, Aa2-066, AHS, Ahsg alpha-2-HS-glycoprotein, Ahsg, Alpha 2 HS Glycoprotein, Alpha 2 Z globulin, and Alpha-2-HS-glycoprotein. It is also referred to as Alpha-2-HS-glycoprotein chain B, Alpha-2-Z-globulin, Asialofetuin, Ba alpha 2 glycoprotein, Ba-alpha-2-glycoprotein, BSP, Countertrypin, Fetua, FETUA_HUMAN, Fetuin (mouse homolog of), Fetuin A, Fetuin-A, Glycoprotein PP63, HSGA, and pp63.
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SourceRabbit
SpecificityOur AHSG Antibody is able to detect the natural levels of total AHSG within an organism. This means that it is capable of accurately measuring the endogenous levels of AHSG in a sample. By using our antibody, researchers can obtain valuable information about the presence and quantity of AHSG in various biological systems.
Species ReactivityHuman;Mouse;Rat
AntigenAHSG
ApplicationThe recommended dilution range for WB is 1:500-1:2000, for IHC it is 1:50-1:200, and for ELISA using a peptide, the dilution range is 1:20000-1:40000. It is important to follow these recommended dilutions to ensure accurate and reliable results for your experiments. Adjusting the dilutions outside of these ranges may result in unexpected outcomes and inconsistencies in your data. By adhering to the recommended dilution ranges, you can achieve consistent and reproducible results for your research.
ImmunogenA synthesized peptide derived from human AHSG.
MW39kDa
Properties

Concentration

1mg/ml

purificationThe antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
ClonalityPolyclonal Antibody
Stability & StorageStore at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage bufferRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Target

Background

Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.

Tissue specificitySynthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.
Posttranslational modificationPhosphorylated by FAM20C in the extracellular medium.O- and N-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan at Asn-156: Hex5HexNAc4; N-glycan heterogeneity at Asn-176: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor).
Celluar localizationEndoplasmic reticulum;Extracellular region or secreted;Golgi apparatus;
UniPortP02765


Western blot analysis of extracts of variouscell lines, using AHSG antibody.


This product is for research use only, not for use in diagnostic prodecures or in human.


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