Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-ACAD9 Polyclonal Antibody#abs138668

Please note that the price mentioned above is for your reference only. For more detailed pricing information, we recommend that you contact our seller, Vecent. Kindly be advised that the content generated using language models may differ significantly from the original text. Therefore, it is...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs138668-100ug	1-2 Weeks	301.0
abs138668-50ug	1-2 Weeks	201.0

Overview
catalog	abs138668
Other names	Acyl CoA dehydrogenase 9, also known as acyl Coenzyme A dehydrogenase family member 9 or very long chain acyl CoA dehydrogenase VLCAD, is a part of the acyl-CoA dehydrogenase family and is located in the mitochondria. Other names include FLJ23533, MGC14452, and NPD002. This protein plays a crucial role in fatty acid metabolism, specifically the breakdown and oxidation of very long-chain fatty acids. The deficiency of this enzyme can lead to a rare genetic disorder called VLCAD deficiency, which affects the body's ability to convert fatty acids into energy, causing muscle weakness, hypoglycemia, and in severe cases, cardiac arrest. Understanding the function of Acyl CoA dehydrogenase 9 is important in diagnosing and treating VLCAD deficiency and other metabolic disorders. Ongoing research aims to uncover the specific mechanisms involved in the regulation and activity of this protein, providing new insights into the complex world of energy metabolism.
Source	Rabbit
Specificity	The ACAD9 Antibody has the ability to detect the overall expression of ACAD9 at endogenous levels. The content mentioned above can be rearranged to uphold the same meaning and information.
Species Reactivity	Human;Mouse;Rat
Antigen	ACAD9
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human ACAD9.
MW	69kDa
Properties
Concentration	1mg/ml
purification	By employing SulfoLink™ Coupling Resin, the purification of the antiserum was conducted through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To keep the product in good condition, it is advised to store it at a temperature of -20 °C for a period of one year. It is important to avoid exposing the product to repeated cycles of freezing and thawing, as it could potentially affect its quality. Therefore, it is recommended to handle the product with care and store it in accordance with the instructions provided. With proper storage, you can ensure that the product remains viable and effective for your needs.
Storage buffer	The storage conditions for Rabbit IgG are as follows: it should be kept in phosphate buffered saline with a pH of 7.4 and a concentration of 150mM NaCl. Additionally, the solution should contain 0.02% sodium azide and 50% glycerol. It is important to store the IgG at a temperature of -20 °C. The stability of the IgG is guaranteed for a period of 12 months from the date of receipt.
Target
Background	Required for mitochondrial complex I assembly (PubMed:20816094, PubMed:24158852). Has a dehydrogenase activity on palmitoyl-CoA (C16:0) and stearoyl-CoA (C18:0). It is three times more active on palmitoyl-CoA than on stearoyl-CoA. However, it does not play a primary role in long-chain fatty acid oxidation in vivo (PubMed:20816094, PubMed:24158852). Has little activity on octanoyl-CoA (C8:0), butyryl-CoA (C4:0) or isovaleryl-CoA (5:0).
Tissue specificity	Ubiquitously expressed in most normal human tissues and cancer cell lines with high level of expression in heart, skeletal muscles, brain, kidney and liver.
Celluar localization	Mitochondrion;Nucleus;
UniPort	Q9H845