Rabbit Anti-67kDa Laminin Receptor Polyclonal Antibody#abs137187
Please note that the price provided is only for your reference. For detailed pricing information, we kindly request you to get in touch with our sales representative, Vecent. Western blot analysis 67kDa Laminin Receptor ? using COS7 whole cell lysates This product is for research use only, not...
Description
| Catalog-specification | Delivery time | USD price |
abs137187-100ug | 1-2 Weeks | 301.0 |
abs137187-50ug | 1-2 Weeks | 201.0 |
Please note that the price provided is only for your reference. For detailed pricing information, we kindly request you to get in touch with our sales representative, Vecent.
| Overview | |
catalog | abs137187 |
| Other names | The laminin receptor is a protein found in various forms, including the 34/67 kDa laminin receptor, 37 kDa laminin receptor precursor, and 37/67 kDa laminin receptor. It is also known as 37LRP, 40S ribosomal protein SA, or 67 kDa laminin receptor. Another name for it is the colon carcinoma laminin binding protein or LAMBR. It is sometimes referred to as Laminin receptor 1 or LBP. The laminin receptor plays a role in colon carcinoma, and it is also associated with multidrug resistance, as seen in the multidrug resistance associated protein MGr1 Ag or MGr1Ag. Additionally, it is known as NEM/1CHD4 or p40. Overall, the laminin receptor is an important protein with various functions and roles. |
| Source | Rabbit |
| Specificity | The 67kDa Laminin Receptor Antibody is capable of accurately detecting the overall levels of endogenous 67kDa Laminin Receptor. This means that it can recognize and bind to the target protein regardless of its level of expression within the sample. Therefore, it provides a reliable way of assessing the total amount of 67kDa Laminin Receptor present in a given sample. |
| Species Reactivity | Human;Mouse;Rat |
| Predictive reaction species | Chicken;Rabbit;Zebrafish;Dog;Horse |
| Antigen | 67kDa Laminin Receptor |
| Application | WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000 |
| Immunogen | A peptide synthesized from the 67kDa Laminin Receptor in humans has been developed. The synthesized peptide is closely related to the original text information and is based on the research on this crucial protein. This molecule is of significant interest to medical researchers, as it plays a critical role in cellular signaling and cell adhesion. This synthesized peptide will allow further exploration of the biological functions of this protein and its effects on different diseases, including cancer, Alzheimer's disease, and neurological disorders. Through this research, medical scientists may be able to develop new treatments that target the functions of this essential protein. |
| MW | 33 kDa |
| Properties | |
Concentration | 1mg/ml |
| purification | SulfoLink™ Coupling Resin was utilized in the peptide affinity chromatography process to purify the antiserum. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles |
| Storage buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
Target | |
Background | Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. |
| Posttranslational modification | Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association (PubMed:9581863).Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions. |
| Celluar localization | Cytosol;Extracellular region or secreted;Nucleus;Plasma Membrane; |
| UniPort | P08865 |
Western blot analysis 67kDa Laminin Receptor ? using COS7 whole cell lysates
This product is for research use only, not for use in diagnostic prodecures or in human.
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