Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

BCL6 Polyclonal Antibody #abs117706

Please note that the price provided is only for your reference. For detailed pricing information, we recommend that you reach out to our seller, Vecent. We want to ensure that you receive the most accurate and up-to-date pricing information possible, so please speak directly with our...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs117706-50ul	In Stock	228

Overview
Other names	BCL5;BCL6A;LAZ3;ZBTB27;ZNF51
Source	Rabbit
Species Reactivity	Human,Mouse
Application	WB 1:500 - 1:2000 IF 1:50 - 1:100
Immunogen	A fusion protein of human origin, containing a corresponding sequence to amino acids 1-280 of the BCL6 protein (NP_001697.2), has been created through the process of genetic recombination. This recombinant fusion protein is structurally similar to its native counterpart and may be useful in various scientific and medical applications. The precise details of the cloning and expression of this protein are available in the relevant research literature.
Properties	Raji,Jurkat,Mouse lung
Properties
Purification	Affinity purification
Clonality	Polyclonal Antibody
Isotype	IgG
Stability & Storage	Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer	Store at -20℃. Avoid freeze / thaw cycles. pH 7.3 PBS buffer containing 0.02% sodium azide and 50% glycerol is what we have here. This formulation is commonly used in various biological experiments. It is important to note that sodium azide serves as a preservative to inhibit microbial growth, while glycerol acts as a cryoprotectant to prevent damage during freezing and thawing processes. The pH of 7.3 ensures optimal conditions for biological reactions and compatibility with many biological systems. Overall, this PBS buffer with a specific composition finds wide application in research laboratories.
Target
Background	This gene codes for a zinc finger transcription factor that features a POZ domain at its N-terminus. As a sequence-specific transcriptional repressor, this protein regulates the transcription of STAT-dependent IL-4 responses of B cells. Moreover, it can bind with POZ-containing proteins that function as transcription corepressors. Interestingly, this gene is frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL). Consequently, it is speculated to be involved in the pathogenesis of DLCL. Additional transcript variants that encode different protein isoforms have been identified via alternative splicing.
Celluar localization	Nucleus
UniPort	P41182

Data Examples

Western blot analysis of extracts of various cell lines, using BCL6 antibody (abs117706) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 30s.