Recombinant Human Prolactin #abs01322

abs01322-10ug

4 Weeks

189

abs01322-50ug

4 Weeks

481

abs01322-1mg

4 Weeks

4782

Description

Recombinant Human Prolactin is a hormone that plays a crucial role in both the brain and the body. While it is produced primarily by the pituitary gland, it is also synthesized by other cells such as the placenta, uterus, and brain. Its main function is to support lactation and ensure the ongoing production of breast milk.
However, recent research has revealed that this hormone does far more than just support breastfeeding. It has also been implicated in issues such as breast cancer development, regulation of reproductive function, and immunoregulation.
In light of these findings, it is clear that Recombinant Human Prolactin is a multifaceted hormone with numerous functions and implications for human health. By better understanding its effects on the body and mind, we can develop new strategies for treating a range of medical conditions, from lactation issues to cancer and beyond.

The human recombinant Prolactin produced in E.Coli is a pure and non-glycosylated protein consisting of 200 amino acids, with a molecular weight of 23007 Dalton. This Prolactin is extracted using exclusive chromatographic procedures ensuring its high quality and purity.

Other names

Mammotropin, Luteotropic hormone, Luteotropin, PRL, or Recombinant Human Prolactin are all different names for the same hormone. This hormone is produced by the pituitary gland and has many functions in the body. One of its primary roles is to stimulate milk production in women after childbirth. In addition to this, it also plays a role in regulating the immune system, metabolism, and behavior. Because of its diverse functions, it is important for researchers to continue studying this hormone and its effects on the body. Scientists have developed recombinant forms of prolactin that can be used for research purposes. These forms of the hormone are highly similar to naturally occurring prolactin, and allow researchers to study its effects in a controlled environment. Overall, prolactin is a fascinating hormone with many important functions in the body.

Properties

Concentration

Greater than 95.0% as determined by:

(a) Analysis by SEC-HPLC.

(b) Analysis by SDS-PAGE.

Activity

The specific activity of 15,385,000IU/mg was observed when determining the ED50 using the dose-dependant stimulation of rat lymphoma, Nb2-11. The resulting value was found to be less than 0.065ng/ml. This information gives insight into the potency and effectiveness of the substance being tested in promoting the proliferation of the lymphoma cells. Understanding these measurements is critical in evaluating the potential usefulness of the substance for further experimentation or therapeutic development.

Reconstitution

To prepare the lyophilized Prolactin for use, follow these guidelines. The protein was initially concentrated to 1mg/ml and subsequently lyophilized. It was stored in a solution containing 10mM sodium Phosphate buffer with a pH of 8 and 50mM NaCl. For reconstitution, it is essential to use sterile 18MΩ-cm H2O, ensuring a minimum concentration of 100µg/ml. This reconstituted solution can then be further diluted with other aqueous solutions as needed. This procedure ensures the proper preparation and utilization of the Prolactin protein.

Stability & Storage

Prolactin in lyophilized form can be stored at room temperature for up to 3 weeks, but it is recommended to store it in a desiccated condition below -18°C. When reconstituted, Prolactin should be kept at a temperature of 4°C for a period of 2-7 days. For long-term storage, it is advisable to store it below -18°C.

For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Please prevent freeze-thaw cycles.