6-Phosphogluconate Dehydrogenase Microplate Assay Kit

The enzyme phosphogluconic acid dehydrogenase, also known as 6-phosphogluconic dehydrogenase, 6-phosphogluconic carboxylase, 6-phosphogluconate dehydrogenase (decarboxylating), or 6-phospho-D-gluconate dehydrogenase, plays an important role in the regulation of glucose metabolism. This enzyme catalyzes the oxidation of 6-phosphogluconate to produce ribulose-5-phosphate and carbon dioxide, which serves as a major source of NADPH for biosynthetic processes in the cell. The activity of this enzyme is essential for the proper functioning of several metabolic pathways, including the pentose phosphate pathway and the biosynthesis of nucleotides and fatty acids. Genetic defects in this enzyme have been associated with various diseases, including hemolytic anemia and metabolic disorders. Understanding the structure and function of this enzyme is critical for developing new therapies for these conditions.

The activity of 6-Phosphogluconate Dehydrogenase can be detected and quantified using specific methods. This enzyme plays a crucial role in the pentose phosphate pathway and its activity measurement is essential for various biochemical studies. By rearranging the given content, we can provide the following alternative text:
To determine and measure the activity of 6-Phosphogluconate Dehydrogenase, several techniques can be employed. The quantification of this enzyme's activity is particularly important in studying the pentose phosphate pathway and its associated metabolic processes. Various methods have been developed specifically for the detection and measurement of 6-Phosphogluconate Dehydrogenase activity, allowing researchers to gain valuable insights into its role and regulation in cellular metabolism.

4 umol/L - 400 umol/L

Shipped and store at 4°C for 6 months.