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Rabbit Anti-TRAK2 Polyclonal Antibody#abs139483

Please note that the price mentioned above is only for your reference. For detailed pricing information, kindly get in touch with our seller Vecent. Western blot analysis TRAK2 using LOVO whole cell lysates This product is for research use only, not for use in diagnostic prodecures or in human.

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Description

Catalog-specification	Delivery time	USD price
abs139483-100ug	1-2 Weeks	301.0
abs139483-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is only for your reference. For detailed pricing information, kindly get in touch with our seller Vecent.

Overview
catalog	abs139483
Other names	Candidate gene ALS2CR3, also known as Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 3, is responsible for the juvenile onset of amyotrophic lateral sclerosis. The protein encoded by this gene is known as trafficking kinesin-binding protein 2 or GRIF1, and plays a critical role in intracellular transport by binding to kinesin motor proteins to facilitate organelle movement. TRAK2, as it is also referred to, is an essential protein for neuron development and function, including synaptic plasticity, growth, and survival. Its dysfunction has been linked to various neurological conditions, such as Alzheimer's disease. In addition to its vital role in nervous system function, TRAK2 also has non-neuronal functions, playing a crucial role in the regulation of autophagy and adipocyte differentiation. CALS C and OIP98 are additional names for this protein, indicating its broader impact on cellular processes beyond the nervous system.
Source	Rabbit
Specificity	The TRAK2 Antibody has the ability to identify total TRAK2 levels within the body. This means that it is capable of detecting the natural concentration of TRAK2 in biological systems. To produce a similar content, one could phrase it as follows: The TRAK2 Antibody is effective in detecting endogenous levels of TRAK2. This indicates its capacity to identify the levels of TRAK2 that exist naturally within an organism.
Species Reactivity	Human
Antigen	TRAK2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human TRAK2.
MW	101 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized in the process of peptide affinity chromatography for the purification of the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it's advisable to store it at a temperature of -20 °C for a period of one year. It's important to prevent it from being subjected to repeated cycles of freezing and thawing, as this could compromise its effectiveness and suitability for use. Hence, make sure to handle it carefully and store it in an appropriate manner to ensure its longevity.
Storage buffer	The provided information states that Rabbit IgG should be stored at -20 °C in phosphate buffered saline, pH 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is also mentioned that the antibody remains stable for a period of 12 months from the date of receipt.
Target
Background	May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
Tissue specificity	Widely expressed, with highest expression in heart.
Posttranslational modification	O-glycosylated.
Celluar localization	Endosome;Mitochondrion;Nucleus;Plasma Membrane;
UniPort	O60296