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Rabbit Anti-SYCP1 Polyclonal Antibody#abs132956

Please note that the price provided is only for reference. For detailed pricing information, kindly get in touch with our seller, Vecent. Western blot analysis of SYCP1 expression in MCF7 whole cell lysate ,The lane on the left is treated with the antigen-specific peptide. This product is for...

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Description

Catalog-specification	Delivery time	USD price
abs132956-100ug	1-2 Weeks	301.0
abs132956-50ug	1-2 Weeks	201.0

Please note that the price provided is only for reference. For detailed pricing information, kindly get in touch with our seller, Vecent.

Overview
catalog	abs132956
Description	The synaptonemal complex (SC) is a crucial structure formed during meiotic prophase that facilitates homologous chromosome pairing. One of the key components of the SC are the transverse filaments, which run perpendicular to the longitudinal axis of the chromosome. These filaments link the homologous chromosomes together, ensuring that they remain aligned during the subsequent stages of meiosis. The transverse filaments are essential for the precise segregation of genetic material and the formation of haploid gametes. Overall, the SC and its components play a critical role in ensuring the fidelity of meiotic cell division.
Other names	Testis antigen 8, also known as CT8 or HOM TES 14, is a protein encoded by the MGC104417 gene. It is alternatively named SCP 1, SCP-1, SCP1, SYCP 1, or Sycp1. The human protein, designated as SYCP1_HUMAN, is also referred to as synaptonemal complex protein 1 or testicular tissue protein Li 191. This protein plays a crucial role in the formation of synaptonemal complexes during meiosis.
Source	Rabbit
Specificity	The SYCP1 antibody has the ability to recognize and bind to total endogenous levels of SYCP1. This indicates that the antibody can effectively detect the presence of SYCP1 within a sample.
Species Reactivity	Human;Mouse
Antigen	SYCP1
Application	The recommended dilution range for WB is 1:500-1:2000, for IHC it is 1:50-1:200, and for ELISA with peptide it is 1:20000-1:40000. To ensure accurate results, it is important to follow these dilution guidelines and optimize according to the specific experiment. Dilution factors can be adjusted based on the amount and quality of the sample, as well as the sensitivity of the detection method used. Overall, proper dilution is essential to achieve reliable and reproducible data in various applications.
Immunogen	A synthesized peptide.
MW	114 kDa
Properties
Concentration	1mg/ml
purification	We employed SulfoLink™ Coupling Resin in peptide affinity chromatography to purify the antiserum. Let me provide you with a rephrased version of the original content while maintaining its key information.
Clonality	Polyclonal Antibody
Stability & Storage	It is advised to store at a temperature of -20 °C for a duration of one year while avoiding repeated freeze-thaw cycles. Make sure to follow these guidelines to maintain the quality and stability of the stored items.
Storage buffer	The solution contains rabbit IgG in a buffer of phosphate and saline with a pH of 7.4. It also contains 150mM of NaCl and 0.02% sodium azide, along with 50% glycerol.
Target
Background	Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility.
Tissue specificity	Testis.
Celluar localization	Nucleus;
UniPort	Q15431