Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-SULT1A1 Polyclonal Antibody#abs136010

Please note that the price mentioned above is only for your reference. For detailed pricing information, kindly get in touch with our seller Vecent. It is important to avoid using the same content generation approach as ChapGPT and instead communicate in a manner that produces text that is...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs136010-100ug	1-2 Weeks	301.0
abs136010-50ug	1-2 Weeks	201.0

Overview
catalog	abs136010
Description	SULT1A1, also known as ST1A1, P-PST 1, ST1A3, Ts-PST, P-PST 1, STP and STP1, is a member of the sulfotransferase 1 family. This enzyme is responsible for catalyzing the sulfate conjugation of catecholamines, phenolic drugs, and neurotransmitters. In addition, SULT1A1 plays a vital role in sulfation and activation of minoxidil. Interestingly, it also mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could play a role in modulating cancer risk. SULT1A1 is one of two phenol sulfotransferases with thermostable enzyme activity, making it a unique and important enzyme in various metabolic pathways.
Other names	Sulfotransferase 1A1, also known as Aryl sulfotransferase 1 or HAST1/HAST2, is an important enzyme found in humans. Its mRNA sequence is complete, and it is also referred to as MGC131921 and MGC5163. The gene is also annotated as OTTHUMP00000162568 and OTTHUMP00000162569. Sulfotransferase 1A1 is involved in the sulfation of various compounds, particularly phenol-containing substances. It is often called phenol sulfotransferase 1 or PST. Another name for this enzyme is phenol-sulfating phenol sulfotransferase 1. It belongs to the sulfotransferase family, specifically the cytosolic 1A subgroup. The enzyme has a preference for phenol substrates, which is why it is also known as Sulfotransferase family 1A phenol preferring member 1. Its activity can be characterized as thermostable, thus it is called thermostable phenol sulfotransferase or Ts-PST. Additionally, it is sometimes referred to as TSPST1. Sulfotransferase 1A1 plays an important role in the metabolism and elimination of phenolic compounds in the human body. By catalyzing the sulfation reaction, it aids in the detoxification and elimination of potentially harmful substances. In summary, Sulfotransferase 1A1 is a significant enzyme involved in the sulfation of phenol-containing compounds. Its activity is thermostable and it belongs to the sulfotransferase family 1A. This enzyme is essential for the metabolism and elimination of phenolic substances in the human body.
Source	Rabbit
Specificity	The Total SULT1A1 Antibody is capable of detecting the natural levels of total SULT1A1 within an organism. By rearranging the original content, a new and similar statement is generated.
Species Reactivity	Human;Mouse;Rat
Antigen	SULT1A1
Application	For Western blot, dilute the antibody at a range of 1:500-1:2000. When it comes to immunohistochemistry, dilute the antibody at a range of 1:50-1:200. For ELISA assays that use peptides, dilute the antibody at a range of 1:20000-1:40000. These dilution ranges are recommended for optimal results.
Immunogen	A synthesized peptide derived from human SULT1A1.
MW	34kDa
Properties
Concentration	1mg/ml
purification	The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin .
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Has also estrogen sulfotransferase activity. responsible for the sulfonation and activation of minoxidil. Is Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.
Tissue specificity	Liver, lung, adrenal, brain, platelets and skin.
Celluar localization	Cytosol;
UniPort	P50225