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Rabbit Anti-SLU7 Polyclonal Antibody#abs134632

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Description

Catalog-specification	Delivery time	USD price
abs134632-100ug	1-2 Weeks	301.0
abs134632-50ug	1-2 Weeks	201.0

Overview
catalog	abs134632
Other names	SLU7 is a pre-mRNA-splicing factor that plays a crucial role in step II splicing. It is also known as Pre mRNA splicing factor SLU7 or MGC9280. This splicing factor contains a zinc knuckle motif that is important for its function. In humans, SLU7 is a homolog of the SLU7 splicing factor found in the yeast Saccharomyces cerevisiae. The SLU7 protein is involved in the maturation of pre-mRNA to functional mRNA by removing introns and joining together exons. This crucial process of splicing occurs in the nucleus of eukaryotic cells and is essential for gene expression. The SLU7 splicing factor is highly conserved among different species, indicating its importance in RNA splicing.
Source	Rabbit
Specificity	Total SLU7 levels can be detected using the SLU7 Antibody, which is capable of recognizing endogenous levels of the protein. By rearranging the information provided, it is emphasized that the SLU7 Antibody specifically targets and detects the overall expression of SLU7 in biological samples.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Rabbit;Pig;Dog;Sheep;Bovine;Horse
Antigen	SLU7
Application	For Western Blot, the recommended dilution is 1:500 to 1:1000. For immunofluorescence and immunocytochemistry, the suggested dilution range is 1:100 to 1:500. When using ELISA with the peptide, the advised dilution range is 1:20000 to 1:40000. It is essential to dilute the samples properly to achieve accurate and reliable results.
Immunogen	A synthesized peptide.
MW	65 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was accomplished through peptide affinity chromatography. To produce related content, it can be stated that the antiserum was subjected to a purification process that utilized SulfoLink™ Coupling Resin in order to carry out peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid exposing it to repeated cycles of freezing and thawing as this may compromise its effectiveness. Therefore, it is advised to handle the product with care and store it in appropriate conditions to ensure its longevity.
Storage buffer	The storage conditions for Rabbit IgG are as follows: it should be stored at -20 °C in phosphate buffered saline (pH 7.4) containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This formulation ensures the stability of the antibody for a period of 12 months from the date of receipt. It is important to follow these storage instructions to maintain the integrity and functionality of the Rabbit IgG.
Target
Background	Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.
Celluar localization	Cytosol;Nucleus;
UniPort	O95391