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Rabbit Anti-SENP3 Polyclonal Antibody#abs137675

Please be advised that the mentioned price is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. Western blot analysis SENP3 using HuvEc whole cell lysates This product is for research use only, not for use in diagnostic...

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Description

Catalog-specification	Delivery time	USD price
abs137675-100ug	1-2 Weeks	301.0
abs137675-50ug	1-2 Weeks	201.0

Please be advised that the mentioned price is only for your reference. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.

Overview
catalog	abs137675
Other names	SENP3 is also known as Sentrin / SUMO specific protease 3 or Sentrin specific protease 3. It is an enzyme that specifically acts on Sentrin, SUMO, and SMT3 proteins. SENP3 is involved in the processing and deconjugation of SUMO proteins, playing a critical role in regulating their function. This protease, also referred to as Sentrin-specific protease 3 or SUMO-1-specific protease 3, is encoded by the SENP3_HUMAN gene. It is also called Sentrin/SUMO-specific protease SENP3. Additionally, it is known by other names such as SMT3IP1, SSP3, SUMO 1 specific protease 3, SUMO1 specific protease 3, SUMO1/sentrin/SMT3 specific peptidase 3, and SUSP3, highlighting its association with SUMO and sentrin pathways. Overall, SENP3 is an important enzyme involved in the regulation of SUMO modifications and protein homeostasis.
Source	Rabbit
Specificity	Endogenous levels of total SENP3 can be detected using the SENP3 Antibody. The antibody is designed to specifically recognize and bind to SENP3, allowing for the accurate measurement of its presence in biological samples. This detection method provides researchers with valuable insights into the expression and regulation of SENP3 in various cellular processes. By rearranging the original content, the information remains the same while presenting it in a different manner.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig
Antigen	SENP3
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human SENP3.
MW	65 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the purification of the antiserum was carried out through peptide affinity chromatography. A highly similar content can be generated by rearranging the original text without changing its meaning.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is recommended to store the product at a temperature of -20 °C for a period of one year. Please take care to avoid repeated freeze/thaw cycles, as this may compromise the quality of the product. By following these guidelines, you can help ensure that the product remains stable and effective over time.
Storage buffer	The storage conditions for Rabbit IgG are as follows: it should be stored at -20 °C in phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. This formulation ensures the stability of the product for a period of 12 months from the date of receipt.
Target
Background	Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
Celluar localization	Nucleus;
UniPort	Q9H4L4