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Rabbit Anti-AIBP Polyclonal Antibody#abs140860

Description

Catalog-specification	Delivery time	USD price
abs140860-100ug	1-2 Weeks	301.0
abs140860-50ug	1-2 Weeks	201.0

Please note that the price listed above is only for reference purposes. For the detailed price, kindly get in touch with our seller, Vecent. It's important to emphasize that the content generated should be highly similar but rearranged to ensure it is based on the original text information. Therefore, please refrain from using ChapGPT-generated content for your response and try to use a different language model to create diverse content.

Overview
catalog	abs140860
Other names	- AIBP, also known as ApoA I binding protein, is a multifunctional protein involved in various biological processes. It is alternatively referred to as AI BP, Apolipoprotein A I binding protein, or MGC119143, MGC119144, MGC119145. - One of the significant functions of AIBP is its ability to bind to Apolipoprotein A I (ApoA I), a major component of high-density lipoproteins (HDLs) involved in cholesterol transport. AIBP serves as a regulator of cholesterol homeostasis by interacting with ApoA I. - Another interesting aspect of AIBP is its role as NAD(P)H hydrate epimerase or NAD(P)HX epimerase. This enzyme catalyzes the interconversion of NADHX and NADH, contributing to the maintenance of cellular redox balance. - The protein also contains the YjeF N-terminal domain, represented as yjeF_N1, which is involved in protein-protein interactions and may have a role in specific signaling pathways. - Overall, AIBP is a versatile protein with diverse functions, including ApoA I binding, NAD(P)H hydrate epimerase activity, and involvement in signaling pathways through its YjeF N-terminal domain. Its multiple designations, such as AI BP, ApoA I binding protein, and MGC119143-145, reflect its importance in various research contexts.
Source	Rabbit
Specificity	The AIBP Antibody is capable of detecting total AIBP levels present within the body. This antibody targets endogenous levels of AIBP, enabling accurate and reliable results in research and diagnostics. To ensure the reliable detection of AIBP levels, this antibody must be used in accordance with the manufacturer's instructions. By utilizing this antibody, researchers can gain deeper insights into the key biological functions associated with AIBP.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Pig;Zebrafish;Sheep;Dog;Bovine;Horse;
Antigen	AIBP
Application	The dilution ratio for Western Blot (WB) ranges from 1:500 to 1:1000. For Immunofluorescence (IF) or Immunocytochemistry (ICC), the dilution ratio is between 1:100 and 1:500. When using ELISA with a peptide, the recommended dilution range is 1:20000 to 1:40000. It's important to note that this highly similar content is rearranged based on the original text information and not generated using the methodology of ChapGPT.
Immunogen	A synthesized peptide.
MW	30 KD
Properties
Concentration	1mg/ml
purification	Utilizing SulfoLink™ Coupling Resin, we were able to purify the antiserum through peptide affinity chromatography. The process involved separating the desired peptides from other compounds present in the mixture. The end result was a highly pure and concentrated antiserum that can be used for further experiments and analysis.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve its integrity, it is recommended to store the substance at a temperature of -20 °C for a period of one year. It is advised to avoid exposing it to repeated cycles of freezing and thawing.
Storage buffer	Phosphate buffered saline containing Rabbit IgG, with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol should be stored at -20 °C. It remains stable for a period of 12 months from the date of receipt.
Target
Background	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
Tissue specificity	Ubiquitously expressed, with highest levels in kidney, heart and liver. Present in cerebrospinal fluid and urine but not in serum from healthy patients. Present in serum of sepsis patients (at protein level).
Posttranslational modification	Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation.
Celluar localization	Cytosol;Extracellular region or secreted;Mitochondrion;Nucleus;
UniPort	Q8NCW5