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Rabbit Anti-PROP1 Polyclonal Antibody#abs132988

Description

Catalog-specification	Delivery time	USD price
abs132988-100ug	1-2 Weeks	301.0
abs132988-50ug	1-2 Weeks	201.0

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Overview
catalog	abs132988
Other names	Pituitary specific homeodomain factor, also known as prophet of Pit 1 or PROP 1, is a paired-like homeodomain transcription factor encoded by the CPHD2 gene. Its alternate name, Homeobox protein prophet of Pit 1, highlights its role as a crucial factor in the development and function of the pituitary gland. The protein coded by the OTTHUMP00000161487 gene plays a significant role in regulating gene expression in pituitary cells. The unique homeodomain structure of PROP 1 enables it to bind specific DNA sequences and control the expression of target genes involved in pituitary development. Understanding the functions and mechanisms of this protein is of great importance in deciphering the complex processes that underlie pituitary gland formation and function.
Source	Rabbit
Specificity	The endogenous levels of total PROP1 can be accurately detected by the PROP1 antibody.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Zebrafish;Rabbit;Pig;Dog;Horse;Sheep;Bovine
Antigen	PROP1
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	25 kDa
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography using SulfoLink™ Coupling Resin was employed to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To keep the product in good condition, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to prevent the product from undergoing repeated freeze and thaw cycles, as this can lead to degradation of the product. By following these storage guidelines, you can ensure that the product remains stable and effective for its intended use.
Storage buffer	The solution contains Rabbit IgG, which is suspended in a phosphate buffered saline solution with a pH of 7.4, 150mM NaCl, and 0.02% sodium azide. Additionally, the solution is made up of 50% glycerol to help maintain the integrity of the protein. This composition ensures the stability of the Rabbit IgG, allowing it to be used in various applications. It should be noted that the solution contains a small amount of sodium azide, which is toxic if ingested, therefore proper precautions should be taken when handling the solution.
Target
Background	Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.
Tissue specificity	Expressed specifically in embryonic pituitary.
Celluar localization	Nucleus;
UniPort	O75360