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Rabbit Anti-PKR2 Polyclonal Antibody#abs139784

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Description

Catalog-specification	Delivery time	USD price
abs139784-100ug	1-2 Weeks	301.0
abs139784-50ug	1-2 Weeks	201.0

Overview
catalog	abs139784
Other names	The protein encoded by B830005M06Rik is known by several names, including dJ680N4.3, EG-VEGRF2, G protein coupled receptor 73 like 1, G protein coupled receptor I5E, G-protein coupled receptor 73-like 1, GPR73b, GPR73L1, GPRg2, HH3, KAL3, PK R2, PK-R2, PKR2, and Prokineticin receptor 2. This receptor is involved in signaling pathways that regulate various physiological processes. It belongs to the G protein-coupled receptor family and specifically binds to prokineticins, which are small neuropeptides that modulate pain perception, circadian rhythms, and reproductive functions. Mutations in this gene have been linked to Kallmann syndrome, a genetic disorder that involves impaired olfactory and reproductive system development. Overall, Prokineticin receptor 2 plays an important role in multiple biological functions and is a potential therapeutic target for various diseases.
Source	Rabbit
Specificity	The endogenous levels of total PKR2 can be detected using the PKR2 Antibody. By utilizing this antibody, researchers can accurately measure the amount of PKR2 present within a biological sample. This facilitates the study of PKR2 and its role in various physiological processes.
Species Reactivity	Human;Mouse;Rat
Antigen	PKR2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human PKR2.
MW	44 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed for peptide affinity chromatography to purify the antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is advisable to store it at a temperature of -20 °C for a period of one year. It is important to avoid exposing the product to repeated cycles of freezing and thawing, as this may impact its effectiveness. Proper storage and handling are crucial to ensure the product's reliability and longevity. Take care to follow all instructions and precautions to maximize the benefits of this product.
Storage buffer	The Rabbit IgG is stored in a solution of phosphate buffered saline, pH 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store the solution at a temperature of -20 °C. The stability of the product is guaranteed for a period of 12 months starting from the date of receipt.
Target
Background	Receptor for prokineticin 2. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase.
Tissue specificity	Expressed in the ileocecum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary and brain.
Celluar localization	Plasma Membrane;
UniPort	Q8NFJ6