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Rabbit Anti-PHACTR4 Polyclonal Antibody#abs134591

Please note that the price mentioned above is provided for your reference only. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent. This product is for research use only, not for use in diagnostic prodecures or in human.

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Description

Catalog-specification	Delivery time	USD price
abs134591-100ug	1-2 Weeks	301.0
abs134591-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is provided for your reference only. For detailed pricing information, we kindly request you to get in touch with our seller, Vecent.

Overview
catalog	abs134591
Other names	Phactr4, also known as phosphatase and actin regulator 4, is a protein found in humans. Its gene is called PHAR4. Phactr4 is involved in the regulation of cellular processes related to actin, which is a protein involved in cellular movement. It also functions as a phosphatase, which means it can remove phosphate groups from other molecules in the cell. Overall, Phactr4 plays an important role in maintaining the structure and function of cells in the human body.
Source	Rabbit
Specificity	Total PHACTR4 expression levels can be detected using the PHACTR4 Antibody, which is capable of recognizing endogenous PHACTR4 protein. To produce similar content, the sentence structure and vocabulary may be altered while retaining the key information.
Species Reactivity	Human
Predictive reaction species	Rabbit
Antigen	PHACTR4
Application	WB 1:500~1:1000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	80 KD
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography with SulfoLink™ Coupling Resin was utilized to purify the antiserum. Let's generate a highly similar content by rearranging the provided information, while ensuring it is based on the original text.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the longevity of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated freeze/thaw cycles.
Storage buffer	The rabbit IgG comes in a solution of phosphate buffered saline with a pH of 7.4, and also contains 150mM of NaCl and 0.02% sodium azide. To prevent degradation, the solution is mixed with 50% glycerol and stored at a temperature of -20 °C. It is considered stable for a period of 12 months after being received.
Target
Background	Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to dephosphorylation and subsequent activation of cofilin (COF1 or COF2) and repression of the integrin signaling through the RHO/ROCK pathway (By similarity).
UniPort	Q8IZ21