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Rabbit Anti-Oxr1 Polyclonal Antibody#abs140502

Description

Catalog-specification	Delivery time	USD price
abs140502-100ug	1-2 Weeks	301.0
abs140502-50ug	1-2 Weeks	201.0

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Overview
catalog	abs140502
Other names	The human protein OXR1, also known as oxidation resistance protein 1, plays a crucial role in protecting the cell from oxidative stress. Its function is closely linked to nucleolar protein C7, which is encoded by the gene Nbla00307. This putative protein product has been studied in various organisms and is known for its remarkable ability to resist oxidation. One of the key features of OXR1 is its ability to regulate the expression of genes involved in oxidative stress response. This is achieved through its interaction with C7B, a related protein that has been shown to play a role in nucleolar function. Additionally, OXR1 has been found to be important for cell survival under conditions of high oxidative stress. Studies have also shown that OXR1 is involved in a range of cellular processes, including DNA damage repair, autophagy, and cell signaling. Its intricate network of interactions with other proteins underscores its essential role in maintaining cellular homeostasis. In summary, OXR1, C7, and related proteins play a critical role in protecting cells from oxidative stress and ensuring their survival in harsh environments. Their importance in cellular function and homeostasis make them attractive targets for developing therapeutics to combat a range of diseases, including cancer and neurodegeneration.
Source	Rabbit
Specificity	The Oxr1 Antibody is capable of detecting total Oxr1 levels present within the body. This detection is done on an endogenous level. A similar piece of content can be generated by rearranging the given text information in a new way, but maintaining its accuracy.
Species Reactivity	Human;Mouse
Predictive reaction species	Horse;Dog;
Antigen	Oxr1
Application	WB 1:1000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human Oxr1.
MW	85kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was used to purify the antiserum through peptide affinity chromatography. Please provide alternative content that maintains the core information while rearranging the structure.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is advised to keep the product at a temperature of -20 °C for a maximum of one year. It is important to note that repeated freeze and thaw cycles should be avoided in order to maintain the product's integrity. Therefore, proper storage and handling of the product is crucial to prolong its shelf life and maintain its quality.
Storage buffer	The recommended storage condition for Rabbit IgG is at -20 °C in phosphate buffered saline solution with a pH of 7.4. The solution contains 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is advised to store the product under these conditions for a maximum of 12 months from the date of receipt to ensure its stability.
Target
Background	May be involved in protection from oxidative damage.
Tissue specificity	By heat shock and oxidative stress.
Celluar localization	Mitochondrion;Nucleus;
UniPort	Q8N573