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Rabbit Anti-NeuN Polyclonal Antibody#abs135665

Description

Catalog-specification	Delivery time	USD price
abs135665-100ug	1-2 Weeks	301.0
abs135665-50ug	1-2 Weeks	201.0

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Overview
catalog	abs135665
Description	FOXP3, also known as NeuN or RBFOX3, is a specific nuclear protein predominantly found in neurons, weighing approximately 38-50kd with the most common weight being around 48kd. Belonging to a family of 3 mammalian Fox homologues, FOX3 serves as an essential RNA-binding protein involved in the regulation of alternative splicing events.
Other names	FLJ56884, FLJ58356, Fox-1 homolog C, fox1 homolog C, Fox3, FOX3NeuN, hexaribonucleotide binding protein 3, HRNBP3, NEUN, neuronal nuclei, Rbfox3, RFOX3_HUMAN, RNA binding protein fox-1 homolog 3, RNA binding protein, fox 1 homolog (C. elegans) 3. Here are some rearranged versions of the content: 1. The RNA binding protein, fox1 homolog C, also known as Fox-1 homolog C or Fox3, is encoded by the FLJ56884 and FLJ58356 genes. It is involved in hexaribonucleotide binding and is also referred to as HRNBP3 or NEUN. Rbfox3, or neuronal nuclei, is another name for this protein. The RFOX3_HUMAN gene encodes the RNA binding protein fox-1 homolog 3, which plays a role in cellular processes. 2. Fox1 homolog C, also known as Rbfox3, is an RNA binding protein encoded by FLJ56884 and FLJ58356 genes. It is a hexaribonucleotide binding protein involved in neuronal nuclei. Additionally, it is referred to as Fox-1 homolog C, Fox3, or FOX3NeuN. The HRNBP3 or NEUN gene is responsible for encoding this protein and is classified as an RNA binding protein, fox 1 homolog (C. elegans) 3. 3. The FLJ56884 and FLJ58356 genes encode Fox1 homolog C, a hexaribonucleotide binding protein. This protein, also known as Fox3 or FOX3NeuN, is involved in neuronal nuclei. It is encoded by the HRNBP3 or NEUN gene and is classified as an RNA binding protein fox-1 homolog 3. Additionally, it is referred to as Rbfox3 or RNA binding protein, fox 1 homolog (C. elegans) 3. Please note that the generated content is for informational purposes only and should be verified with reliable sources.
Source	Rabbit
Specificity	The endogenous levels of total NeuN can be detected using the NeuN Antibody.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Chicken;Rabbit;Pig;Dog;Sheep;Horse;Bovine
Antigen	NeuN
Application	The dilution ranges for Western Blot (WB) are 1:500-1:2000, for Immunohistochemistry (IHC) are 1:50-1:200, and for ELISA (peptide) are 1:20000-1:40000. These dilutions determine the optimal concentrations at which these techniques should be performed for accurate results. It is important to follow these dilution guidelines in order to obtain reliable data during experiments.
Immunogen	A synthesized peptide derived from human NeuN.
MW	34kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. To ensure a highly refined and effective final product, this method was selected.
Clonality	Polyclonal Antibody
Stability & Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD).
Celluar localization	Nucleus;
UniPort	A6NFN3