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Rabbit Anti-MYOM2 Polyclonal Antibody#abs141274

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Description

Catalog-specification	Delivery time	USD price
abs141274-100ug	1-2 Weeks	301.0
abs141274-50ug	1-2 Weeks	201.0

Overview
catalog	abs141274
Other names	The 165 kDa connectin-associated protein, also known as 165 kDa titin-associated protein, M-band protein, or M-protein, is a crucial component of the myofibril that contributes to the structural integrity of muscle fibers. MYOM2, or myomesin 2, is a protein coding gene that encodes the 165kD isoform of myomesin, which interacts with titin and other myofibril proteins to form the M-line of sarcomeres. This family member 2 protein is essential for maintaining muscle contractile properties and is involved in the organization of the muscle sarcomere. Titin-associated protein 165 kD, also known as TTNAP, is a highly conserved protein that functions as a molecular scaffold, connecting the myosin thick filaments and the actin thin filaments, ultimately contributing to the mechanical force generation in muscle. In summary, the 165 kDa connectin-associated protein, myomesin 2, and titin-associated protein play significant roles in maintaining the structural integrity and contractile properties of muscle fibers.
Source	Rabbit
Specificity	The MYOM2 Antibody has the ability to detect total MYOM2 levels in the body. It works by identifying the endogenous levels of this protein. In essence, the MYOM2 Antibody is a powerful tool that can help researchers study the properties and behavior of this protein in great detail. By gaining a better understanding of MYOM2, scientists may be able to develop new treatments for various diseases and conditions.
Species Reactivity	Human;Mouse
Predictive reaction species	Rabbit;Bovine;Sheep
Antigen	MYOM2
Application	The recommended dilution ratio for Western blotting is 1:500~1:1000, while for immunofluorescence or immunocytochemistry it is 1:100-1:500. For ELISA using a peptide, the suggested dilution range is 1:20000-1:40000. Ensure that you adhere to these guidelines when performing experiments to achieve accurate and reliable results.
Immunogen	A synthesized peptide.
MW	165 KD
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent peptide affinity chromatography for purification. I can generate highly similar content by rearranging the information from the above text. However, please note that the generated content will be based on the original text information and will not deviate significantly from it.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the integrity of the product, it is recommended to store it at -20 °C for a duration of one year. To prevent any potential damage, it is advisable to avoid frequent freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.
Celluar localization	Cytoskeleton;Mitochondrion;
UniPort	P54296