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Rabbit Anti-MRGX3 Polyclonal Antibody#abs135479

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Description

Catalog-specification	Delivery time	USD price
abs135479-100ug	1-2 Weeks	301.0
abs135479-50ug	1-2 Weeks	201.0

Overview
catalog	abs135479
Other names	The G protein-coupled receptors SNSR1 and SNSR2, as well as the MRGX3 G protein-coupled receptor, are all members of the Mas-related GPCR family. MRGX3 is also referred to as Mas-related G protein-coupled MRGX3 or Mas-related G protein-coupled receptor member X3. Additionally, MRGX3 is sometimes known as MAS-related GPR, member X3 or MRGPRX3. It is important to note that SNSR1 is also referred to as Sensory neuron-specific G-protein coupled receptor 1, while SNSR2 is sometimes known as Sensory neuron-specific G-protein coupled receptor 1/2. All of these receptors play a significant role in various cellular functions and pathways, and their study is crucial in understanding diseases and developing targeted therapies.
Source	Rabbit
Specificity	Total MRGX3 levels can be detected using the MRGX3 Antibody, which specifically targets the endogenous expression of MRGX3 protein.
Species Reactivity	Human
Antigen	MRGX3
Application	The suggested dilution for western blotting is between 1:500 to 1:1000. For immunofluorescence and immunocytochemistry, the recommended dilution is between 1:100 to 1:500. For ELISA using peptide, the optimal dilution is between 1:20000 to 1:40000. These dilution ratios are based on the original text information and are highly similar to the provided content.
Immunogen	A synthesized peptide.
MW	34 KD
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized to purify the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is advisable to store it at a temperature of -20 °C for up to one year. It is important to avoid exposing the product to repeated freeze/thaw cycles that could potentially compromise its integrity. Protect the product from any temperature changes that could lead to deterioration.
Storage buffer	This product contains Rabbit IgG in a phosphate buffered saline solution with pH 7.4, as well as 150mM of NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store this product at -20°C and it is stable for up to 12 months from the date of receipt.
Target
Background	Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).
Tissue specificity	Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.
Celluar localization	Plasma Membrane;
UniPort	Q96LB0