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Rabbit Anti-MHC Class1 Polyclonal Antibody#abs133274

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Description

Catalog-specification	Delivery time	USD price
abs133274-100ug	In Stock	301.0
abs133274-50ug	In Stock	201.0

Overview
catalog	abs133274
Other names	The HLA class I histocompatibility antigen, A 1 alpha chain, also known as HLAA or Leukocyte antigen class I A, is an antigen presenting molecule. It is a part of the Major Histocompatibility Complex (MHC) and belongs to the class I antigens. The HLA A heavy chain is an integral component of MHC class I antigen, responsible for presenting antigens to T cells for immune recognition.
Source	Rabbit
Specificity	The detection of total MHC class 1 endogenous levels is achieved using an antibody specific to MHC class 1. Generating a highly similar content by rearranging the above information, it can be stated that the antibody designed for MHC class 1 is capable of identifying and measuring the levels of total MHC class 1 that naturally occur within an organism. This detection method relies on the ability of the antibody to bind specifically to the MHC class 1 molecules, providing valuable insights into the overall expression and abundance of these proteins.
Species Reactivity	Human;Rat;Monkey
Antigen	MHC class1
Application	The recommended dilution for Western Blot analysis is 1:1000-3000, while for Immunohistochemistry it is 1:200. Additionally, for Immunocytochemistry/Immunofluorescence and ELISA (peptide), the suggested dilution ranges from 1:20000-1:40000.
Immunogen	A peptide that has been synthesized using a component of human MHC class 1 has been developed. To create a text similar to the original content, the information should be restructured and written in a way that accurately represents the original text.
MW	41kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed in purifying the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Ensure the storage temperature is maintained at -20 °C for a duration of one year, taking care to prevent any freeze/thaw cycles from occurring.
Storage buffer	The Rabbit IgG is stored in a solution containing phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is recommended to store the solution at -20°C. This product has a stable shelf life of 12 months from the date of receipt.
Target
Background	Involved in the presentation of foreign antigens to the immune system.
Posttranslational modification	Polyubiquitinated in a post ER compartment by interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).
Celluar localization	Endoplasmic reticulum;Endosome;Golgi apparatus;Plasma Membrane;
UniPort	P01891