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Rabbit Anti-LFA3 Polyclonal Antibody#abs141226

Please note that the mentioned price is for your reference only. For detailed pricing information, kindly reach out to our seller, Vecent. Western blot analysis of extracts from HuvEc cells, using LFA3 antibody. This product is for research use only, not for use in diagnostic prodecures or in...

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Description

Catalog-specification	Delivery time	USD price
abs141226-100ug	1-2 Weeks	301.0
abs141226-50ug	1-2 Weeks	201.0

Please note that the mentioned price is for your reference only. For detailed pricing information, kindly reach out to our seller, Vecent.

Overview
catalog	abs141226
Other names	LFA-3 (lymphocyte function associated antigen 3), also known as CD58 antigen, is a molecule expressed on the surface of lymphocytes. It plays a crucial role in immune function and cell-to-cell interactions. LFA-3 is a glycoprotein that is involved in various physiological processes. Its presence helps in the adhesion and activation of immune cells, facilitating the formation of immunological synapses. CD58 is an alternative name for LFA-3 and is often used interchangeably. There are several aliases for LFA-3, including FLJ23181 and FLJ43722. The importance of LFA-3 in the immune system cannot be understated, as it contributes significantly to the regulation of immune responses and the maintenance of immune homeostasis. Understanding the functions and mechanisms of LFA-3 is crucial for advancing our knowledge of immunology and developing potential therapeutic interventions.
Source	Rabbit
Specificity	The LFA3 antibody is capable of identifying the overall levels of endogenous LFA3 within the system. Manipulating the original content, create a new sentence conveying the same information.
Species Reactivity	Human
Antigen	LFA3
Application	For Western blotting, a dilution of 1:500 to 1:1000 is recommended. When using immunofluorescence or immunocytochemistry, a dilution of 1:100 to 1:500 is appropriate. For ELISA assays using peptides, a dilution of 1:20000 to 1:40000 is recommended. It's important to follow these guidelines to ensure accurate and reliable results in your experiments.
Immunogen	A synthesized peptide.
MW	28 KD
Properties
Concentration	1mg/ml
purification	Purification of the antiserum was carried out using SulfoLink™ Coupling Resin by employing peptide affinity chromatography. The procedure involved the selective isolation of a specific peptide sequence from the target protein using the resin. This resulted in a highly purified antiserum suitable for further analysis and experimentation.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the quality of the product, it is recommended to keep it stored at a temperature of -20 °C for up to one year. It is important to note that exposing the product to repeated freeze/thaw cycles should be avoided, as this may impact its effectiveness. By following these proper storage protocols, you can ensure that the product remains in its optimal condition.
Storage buffer	The storage condition for Rabbit IgG is in phosphate buffered saline (pH 7.4) with a concentration of 150mM NaCl. It also contains 0.02% sodium azide and 50% glycerol. It is recommended to store it at a temperature of -20°C. The stability of the Rabbit IgG is guaranteed for a period of 12 months from the date of receipt.
Target
Background	Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Celluar localization	Extracellular region or secreted;Plasma Membrane;
UniPort	P19256