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Rabbit Anti-Inhibin Beta-C Polyclonal Antibody#abs138088

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Description

Catalog-specification	Delivery time	USD price
abs138088	1-2 Weeks	201
abs138088	1-2 Weeks	301

Overview
Other names	Activin beta C chain, also known as activin beta-C chain, IHBC, or Inhbc, is a protein that plays a crucial role in various biological processes. It is encoded by the INHBC_HUMAN gene and is a part of the inhibin beta C protein family. Inhibin beta C, or inhibin, beta C, acts as a subunit of activin and inhibin proteins, which are involved in regulating the secretion of follicle-stimulating hormone (FSH) in the pituitary gland. This protein is primarily expressed in the gonads, where it contributes to reproductive functions. The activin beta C chain has been identified as a crucial factor in embryogenesis, cell proliferation, and differentiation. Understanding its function and regulation can provide valuable insights into the development and treatment of various diseases related to reproductive health and cellular growth.
Source	Rabbit
Specificity	The Inhibin β-C Antibody is specifically designed to detect the total amount of endogenous Inhibin β-C.
Species Reactivity	Human;Mouse
Predictive reaction species	Sheep;Bovine;Horse;Rabbit;
Antigen	Inhibin β-C
Application	For Western blotting, a dilution of 1:1000-3000 is recommended, while for immunohistochemistry, a dilution of 1:200 is appropriate. For ELISA using peptides, a dilution range of 1:20000-1:40000 is recommended. These dilution ranges have been determined based on extensive testing and provide optimal results for each application. It is important to carefully follow the recommended dilution ranges to ensure accurate and reliable results. These dilution ranges may vary depending on the specific antibody or peptide being used and should be optimized for each experiment. Overall, the key to success in these types of assays is careful experimental design and optimization to ensure accuracy and reproducibility.
Immunogen	Human Inhibin β-C can be utilized to synthesize a peptide with a highly similar structure. By deriving this peptide from human Inhibin β-C, we can ensure that it retains the essential characteristics and functionalities inherent in its original form. This synthesized peptide holds tremendous potential for applications in various fields, including medicine and biotechnology. Its close resemblance to human Inhibin β-C enables it to interact with specific receptors and modulate key biological processes. Through careful manipulation and rearrangement of the original content, we can harness the unique properties of this synthesized peptide for further research and development.
MW	38 kDa
Properties
Concentration	1mg/ml
purification	To obtain purified antiserum, SulfoLink™ Coupling Resin was utilized in peptide affinity chromatography. This process facilitated the isolation of the desired antibodies from the mixture, leaving behind only the enriched antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the longevity of your product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to note that repeated freeze/thaw cycles should be avoided, as this can have a negative impact on the quality of the product. By following these storage guidelines, you can maintain the effectiveness and potency of your product for the duration of its lifespan.
Storage buffer	This is a description of Rabbit IgG in a salt solution with sodium azide and glycerol, which should be stored at -20°C and can be stable for up to 12 months. The solution has a pH of 7.4 and a concentration of 150mM NaCl. This information is important for those working with rabbit IgG, as it gives them an idea of how to properly store and handle the solution to ensure its effectiveness over time. The sodium azide helps prevent bacterial growth, while the glycerol serves as a stabilizer. Overall, this is a useful solution for research purposes.
Target
Background	Activins and inhibins have opposing functions with regards to the secretion of follitropin in the pituitary gland. Activin stimulates follitropin secretion while inhibin inhibits its secretion. However, these two proteins are involved in regulating a wide range of functions including hypothalamic and pituitary hormone secretion, gonadal hormone secretion, development and maturation of germ cells, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins have been found to exert opposite effects to activins in many of these processes.
Tissue specificity	Expressed in benign prostatic hyperplasia.
Celluar localization	Extracellular region or secreted;
UniPort	P55103