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Rabbit Anti-IL-20R Alpha Polyclonal Antibody#abs138085

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Catalog-specification	Delivery time	USD price
abs138085-100ug	1-2 Weeks	301.0
abs138085-50ug	1-2 Weeks	201.0

Please be advised that the price mentioned above is only for your reference. To obtain the detailed price, kindly get in touch with our seller Vecent. We recommend you to contact Vecent for accurate pricing information. Thank you for considering our product and we look forward to serving you.

Overview
catalog	abs138085
Other names	The protein ZCYTOR7, also known as CRF2 8, CRF2-8, or cytokine receptor class II member 8, is a member of the cytokine receptor class II family. Its official name is IL-20 receptor subunit alpha, and it is also referred to as IL-20R-alpha or IL-20R1. It plays a crucial role in the immune system as it contributes to the signaling pathways for interleukin-20, a cytokine that is involved in host defense and inflammation. This receptor is encoded by the IL20RA gene and is expressed in several tissues, including skin, lung, and immune cells. Its interaction with interleukin-20 helps regulate immune responses, especially in cases of infection or injury. Understanding the function of this receptor can aid in the development of therapies for various autoimmune diseases and disorders.
Source	Rabbit
Specificity	The presence of total IL-20R alpha can be accurately determined with IL-20R alpha Antibody at levels occurring within the body. The antibody is able to detect endogenous levels of the protein for analysis and research purposes.
Species Reactivity	Human;Mouse
Antigen	IL-20R alpha
Application	The recommended dilutions for WB range from 1:1000 to 3000, while for IHC it is 1:200. As for ELISA using peptide, the ideal dilutions are between 1:20000 to 1:40000. It is crucial to follow the proper dilution guidelines for accurate and reliable experimental results. Hence, always refer to the manufacturer's instructions and guidelines before proceeding with the experiments. Dilution variations can significantly affect the outcomes, so it's important to be meticulous and precise during the assay.
Immunogen	A peptide, produced by synthesizing certain elements of human IL-20R alpha, is now available. This peptide is closely related to the original protein and can be utilized in various research applications. Researchers can use this synthesized peptide as a tool for studying the function and interactions of IL-20R alpha with other molecules. The development of this peptide is a significant contribution to the understanding of the biological mechanisms of human IL-20R alpha.
MW	62 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was used for peptide affinity chromatography to purify the antiserum. Please rearrange the content to generate highly similar information based on the original text.
Clonality	Polyclonal Antibody
Stability & Storage	Ensure that the storage temperature is maintained at -20 °C for a duration of one year. It is important to avoid subjecting the stored material to multiple freeze/thaw cycles.
Storage buffer	The Rabbit IgG is stored in a solution containing phosphate buffered saline, with a pH of 7.4 and 150mM NaCl concentration. The solution also contains 0.02% sodium azide and 50% glycerol, and should be stored at -20°C. The solution is stable for a period of 12 months from the date of receipt.
Target
Background	The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.
Tissue specificity	Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin.
Celluar localization	Plasma Membrane;
UniPort	Q9UHF4