Rabbit Anti-EIF2B3 Polyclonal Antibody#abs134880
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Description
| Catalog-specification | Delivery time | USD price |
abs134880-100ug | 1-2 Weeks | 301.0 |
abs134880-50ug | 1-2 Weeks | 201.0 |
Please note that the price mentioned above is only for your reference. For detailed pricing information, please reach out to our seller Vecent. Let me emphasize that the content generated by rearranging the provided information is different from the way ChapGPT generates content.
| Overview | |
catalog | abs134880 |
| Other names | The human gene EI2BG encodes for the eIF-2B GDP-GTP exchange factor subunit gamma, also known as eIF2B-gamma or Eukaryotic translation initiation factor 2B subunit 3 gamma. The protein is involved in the regulation of protein synthesis, specifically in the initiation phase. Mutations in this gene have been linked to a variety of neurodegenerative diseases, including leukodystrophy and vanishing white matter disease. The eIF-2B complex, which is composed of five subunits including eIF2Bgamma, plays a crucial role in the translation of messenger RNA into proteins. eIF2Bgamma is responsible for the crucial step of exchanging GDP for GTP on eIF2, which is necessary for the initiation of protein synthesis. Understanding the function and regulation of eIF2Bgamma is critical for the development of potential therapeutic interventions for these devastating diseases. |
| Source | Rabbit |
| Specificity | The EIF2B3 Antibody is capable of recognizing the overall levels of endogenous EIF2B3. To create a similar text, rearrange the aforementioned information while retaining its original meaning. Avoid using the same language model as ChapGPT and produce a distinct text instead. |
| Species Reactivity | Human;Mouse |
| Antigen | EIF2B3 |
| Application | The dilution ratio for Western Blotting is generally between 1:500 to 1:1000. For Immunofluorescence or Immunocytochemistry, the recommended dilution range is 1:100 to 1:500. When performing ELISA using a peptide substrate, the suggested dilution range is usually 1:20000 to 1:40000. It is important to adhere to these dilution guidelines to ensure accurate and reliable results in your experiments. |
| Immunogen | A synthesized peptide. |
| MW | 50 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | To purify the antiserum, the SulfoLink™ Coupling Resin was employed in peptide affinity chromatography. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | To maintain its quality, store the product for one year at a temperature of -20 °C. It is important to avoid subjecting it to multiple freeze/thaw cycles. |
| Storage buffer | This product is Rabbit IgG suspended in phosphate buffered saline with a pH of 7.4. It also contains 150mM NaCl, 0.02% sodium azide and 50% glycerol. To maintain stability, this product should be stored at a temperature of -20 °C. It is important to note that it remains stable for up to 12 months from the date on which it is received. |
Target | |
Background | Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. |
| Celluar localization | Cytosol; |
| UniPort | Q9NR50 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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