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Rabbit Anti-HPD Polyclonal Antibody#abs137780

Description

Catalog-specification	Delivery time	USD price
abs137780-100ug	1-2 Weeks	301.0
abs137780-50ug	1-2 Weeks	201.0

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Overview
catalog	abs137780
Other names	4 HPPD is an abbreviation for 4-hydroxyphenylpyruvate dioxygenase, which is also referred to as 4 hydroxyphenylpyruvic acid oxidase. It is alternatively known as GLOD3 (glyoxalase domain containing 3), HPD, HPPD_HUMAN, HPPDase, and PPD. The enzyme 4 HPPD plays a crucial role in the metabolism of phenylalanine, an amino acid. It catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid. This enzyme is of significant interest in the field of medicine and biochemistry, as mutations in the HPPD gene can lead to the development of diseases such as tyrosinemia type III. Understanding the mechanism and function of 4 HPPD is essential for uncovering its importance in various biological processes.
Source	Rabbit
Specificity	The endogenous levels of total HPD can be detected using the HPD Antibody.
Species Reactivity	Human
Antigen	HPD
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human HPD.
MW	45 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, we purified the antiserum through peptide affinity chromatography. To accomplish this, we ensured that the peptide and the resin were thoroughly mixed. The antiserum passed through the mixture, and we let it bind to the resin. Afterwards, we gently eluted the antiserum from the resin, thereby obtaining a highly purified antiserum.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the longevity of the product, it is important to store it at a temperature of -20 °C for a period of one year. It is advised to avoid exposing the product to repeated freeze/thaw cycles as this can affect the quality and efficacy of the product. It is crucial to adhere to these storage instructions in order to maintain the integrity of the product.
Storage buffer	The rabbit IgG comes in a solution containing phosphate buffered saline with pH 7.4, 150mM NaCl, and 0.02% sodium azide. It also contains 50% glycerol, which helps to stabilize the solution for storage at -20 °C. This product can be stored for up to 12 months from the date of receipt.
Target
Background	Key enzyme in the degradation of tyrosine.
Celluar localization	Cytosol;Endoplasmic reticulum;Extracellular region or secreted;Golgi apparatus;
UniPort	P32754