Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-GDF3 Polyclonal Antibody#abs137782

Please note that the price stated here is only for your reference. For more detailed pricing information, we advise you to get in touch with our sales representative Vecent. Western blot analysis GDF3 using Jurkat whole cell lysates This product is for research use only, not for use in...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs137782-100ug	1-2 Weeks	301.0
abs137782-50ug	1-2 Weeks	201.0

Please note that the price stated here is only for your reference. For more detailed pricing information, we advise you to get in touch with our sales representative Vecent.

Overview
catalog	abs137782
Other names	Growth/differentiation factor 3, also known as GDF-3 or Vgr2, is a protein encoded by the GDF3 gene in humans. It has been identified as a key regulator of cellular growth and differentiation in a variety of tissues. Another name for this protein is KFS3, and it has been linked to several developmental disorders. The biological function of GDF-3 is not completely understood, but it has been shown to play a crucial role in embryonic development, particularly in the formation of the skeleton and the nervous system. It has also been implicated in the regulation of stem cell differentiation and the maintenance of pluripotency. Several studies have also suggested that GDF-3 may have therapeutic potential in the treatment of certain diseases, such as spinal cord injuries and some forms of cancer. However, further research is needed to fully understand the mechanisms underlying these effects. Overall, GDF-3 is an important protein with diverse functions in various biological processes. Its potential therapeutic applications make it an exciting area of ongoing research in the biomedical sciences.
Source	Rabbit
Specificity	The GDF3 Antibody has the ability to identify the total amount of endogenous GDF3 present in the system. This means that it is effective in detecting all forms of GDF3 protein, regardless of its size or structure. By using this antibody, researchers can accurately measure levels of GDF3 in various samples and gain insights into its role in biological processes.
Species Reactivity	Human;Mouse;Rat
Antigen	GDF3
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human GDF3.
MW	41 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was employed for peptide affinity chromatography in order to purify the antiserum. Let's create a text that presents a highly similar content but rearranges the information structurally, ensuring it is derived from the original text information. "For the purification of the antiserum, a peptide affinity chromatography approach was employed using SulfoLink™ Coupling Resin. This resin facilitated the selective binding and purification of the desired antigens from the antiserum. By coupling the peptides of interest to the resin, we were able to efficiently isolate and purify the specific targets we were focusing on. The process yielded a highly purified antiserum ready for further analysis and application in research and diagnostic applications."
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, store it at a temperature of -20 °C for a year. It is important to avoid subjecting the product to repeated cycles of freezing and thawing. This will ensure that the product remains stable and does not get damaged.
Storage buffer	Storage conditions: This product, Rabbit IgG, should be stored at -20 °C. It is recommended to store it in phosphate-buffered saline with a pH of 7.4. The storage solution should also contain 150mM NaCl, 0.02% sodium azide, and 50% glycerol. These storage conditions are essential for maintaining the stability of the product. It is important to note that this Rabbit IgG is stable for a period of 12 months starting from the date of its receipt.
Target
Background	Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor TDGF1/Cripto (By similarity). Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and TDGF1/Cripto (PubMed:21805089).
Posttranslational modification	Synthesized as large precursor molecule that undergo proteolytic cleavage, releasing the pro-domain from the active, receptor binding, C-terminal region of the molecule.
Celluar localization	Extracellular region or secreted;
UniPort	Q9NR23