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Rabbit Anti-FGF12 Polyclonal Antibody#abs132872

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Description

Catalog-specification	Delivery time	USD price
abs132872-100ug	1-2 Weeks	301.0
abs132872-50ug	1-2 Weeks	201.0

Overview
catalog	abs132872
Description	Involved in the development and functioning of the nervous system, this particular aspect plays a crucial role.
Other names	Fibroblast growth factor 12 (FGF-12), also known as FGF12 or FGF12_HUMAN, is a protein involved in cellular growth and development. It is part of the FGF family and is specifically referred to as FGF12B. FGF-12 is also known as Fibroblast growth factor homologous factor 1 (FHF-1) and has been shown to be a myocyte-activating factor. FGF-12 plays a crucial role in promoting the activation and differentiation of various cell types. It is involved in regulating cell proliferation, migration, and survival. Additionally, FGF-12 has been implicated in the development and function of the heart and nervous system. The protein FGF12B, encoded by the FGF12 gene, belongs to the fibroblast growth factor family and is closely related to other members such as FGF-1 and FGF-2. FGF12B exhibits similar functions to those of other FGF family members, including promoting cell growth, differentiation, and tissue repair. In summary, FGF-12, also known as FGF12 or FGF12B, is an important protein involved in various cellular processes. Its role as a myocyte-activating factor highlights its significance in heart function. Understanding the functions and mechanisms of FGF-12 can provide valuable insights into the regulation of cell growth and development.
Source	Rabbit
Specificity	The detection of endogenous total FGF12 levels is made possible by the FGF12 antibody. This antibody is designed to specifically target and recognize the total amount of FGF12 present in a biological sample. It allows researchers to study the expression and localization of FGF12 in various tissues and cells. By detecting endogenous levels of total FGF12, valuable insights can be gained into the role and function of this important protein in different biological processes.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Xenopus;Chicken;Rabbit;Pig;Dog;Bovine;Sheep;Horse;
Antigen	FGF12
Application	WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	27 kDa
Properties
Concentration	1mg/ml
purification	Peptide affinity chromatography was employed to purify the antiserum utilizing SulfoLink™ Coupling Resin. Generate an alternative version of the content by rearranging the details mentioned above, while maintaining the original information.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality of the product, it is recommended to store it at a temperature of -20 °C for a period of one year. It is important to avoid exposing the product to repeated instances of freezing and thawing. This will help to ensure that the product remains stable and effective for its intended use.
Storage buffer	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Target
Background	Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation.
Tissue specificity	Brain, eye and testis; highly expressed in embryonic retina, olfactory epithelium, olfactory bulb, and in a segmental pattern of the body wall; in adult olfactory bulb, less in cerebellum, deep cerebellar nuclei, cortex and multiple midbrain structures.
Celluar localization	Extracellular region or secreted;Nucleus;
UniPort	P61328