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Rabbit Anti-EIF2S2 Polyclonal Antibody#abs141129

Description

Catalog-specification	Delivery time	USD price
abs141129-100ug	1-2 Weeks	301.0
abs141129-50ug	1-2 Weeks	201.0

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Overview
catalog	abs141129
Other names	This is a list of different names and abbreviations used to describe a protein called eIF-2-beta or Eukaryotic initiation factor 2 beta. This protein is involved in the eukaryotic translation initiation process and plays an important role in protein synthesis. It is also known as EIF2, EIF2B, EIF2beta, and EIF2S2, among other names. The full name of the protein is Eukaryotic translation initiation factor 2 subunit 2 beta 38kDa. Additionally, the protein is sometimes referred to as PPP1R67 because it interacts with a protein phosphatase called PP1.
Source	Rabbit
Specificity	The EIF2S2 Antibody is able to identify total EIF2S2 levels that occur naturally within an organism. It is important to note that this antibody does not specifically target any variant of the protein EIF2S2 but rather the entire protein itself.
Species Reactivity	Human
Antigen	EIF2S2
Application	WB 1:500~1:1000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide.
MW	40 KD
Properties
Concentration	1mg/ml
purification	Utilizing SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain the quality, store at a temperature of -20 °C for a duration of one year. It is crucial to prevent the occurrence of repeated freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Celluar localization	Cytosol;
UniPort	P20042