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Rabbit Anti-DYNC1H1 Polyclonal Antibody#abs138989

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Description

Catalog-specification	Delivery time	USD price
abs138989-100ug	1-2 Weeks	301.0
abs138989-50ug	1-2 Weeks	201.0

Overview
catalog	abs138989
Other names	1. The cytoplasmic dynein 1 heavy chain 1, also known as DHC1, is a critical protein involved in cellular transport. 2. DHC1a, another name for cytoplasmic dynein heavy chain 1, plays a crucial role in intracellular movement. 3. The protein DKFZp686P2245 is an alternative name for DHC1, suggesting its significance in cellular dynamics. 4. DNCH1, also referred to as Dnchc1, is an essential component of cytoplasmic dynein responsible for cargo transport. 5. DNECL, an abbreviation for dynein, cytoplasmic 1, heavy chain 1, highlights the protein's involvement in intracellular transport processes. 6. DYHC, short for dynein heavy chain, cytosolic, denotes the protein's localization within the cell. 7. The cytoplasmic dynein 1, heavy chain 1, identified as a dynein, cytoplasmic-like protein, contributes to cellular movement and transport. 8. HL-3, another name associated with DHC1, emphasizes its role as a heavy chain component of cytoplasmic dynein. 9. The protein KIAA0325 corresponds to DHC1 and is implicated in various cellular processes. 10. The term p22 is used to represent DHC1, indicating its specific molecular weight or size.
Source	Rabbit
Specificity	The total levels of endogenous DYNC1H1 can be effectively detected by the DYNC1H1 Antibody. You can rearrange the content as follows: "The DYNC1H1 Antibody is capable of detecting the total endogenous levels of DYNC1H1 protein."
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Chicken;Rabbit;Pig;Dog;Bovine
Antigen	DYNC1H1
Application	The recommended dilutions for western blot are between 1:1000 to 1:3000, while for immunohistochemistry, a dilution of 1:200 is suggested. For ELISA using peptide, dilutions ranging from 1:20000 to 1:40000 are appropriate. It is vital to adhere to these dilutions to achieve accurate and reliable results in your experiments.
Immunogen	A synthesized peptide derived from human DYNC1H1.
MW	532kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. By utilizing this method, the antiserum was effectively purified.
Clonality	Polyclonal Antibody
Stability & Storage	To maintain its quality, it is recommended to store the product at a temperature of -20 °C for a duration of one year. It is crucial to avoid subjecting the product to multiple cycles of freezing and thawing.
Storage buffer	The recommended storage conditions for Rabbit IgG are at -20 °C in phosphate-buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to note that this product remains stable for a period of 12 months from the date of receipt.
Target
Background	Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Plays a role in mitotic spindle assembly and metaphase plate congression (PubMed:27462074).
Celluar localization	Cytoskeleton;Cytosol;Extracellular region or secreted;Lysosome;
UniPort	Q14204