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Rabbit Anti-DENND4A Polyclonal Antibody#abs138919

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Description

Catalog-specification	Delivery time	USD price
abs138919-100ug	1-2 Weeks	301.0
abs138919-50ug	1-2 Weeks	201.0

Overview
catalog	abs138919
Other names	Protein-binding promoter of C-myc; DENN-containing protein 4A; DENN domain containing protein 4A; DENND4A; FLJ33949; IRLB; KIAA0476; MYC promoter-binding protein; MYCPP_HUMAN.
Source	Rabbit
Specificity	The total DENND4A levels present in the body can be accurately measured using the DENND4A Antibody. This antibody specifically targets and identifies the endogenous levels of DENND4A protein. It is a reliable tool for detecting the overall expression of DENND4A in biological samples.
Species Reactivity	Human;Mouse
Antigen	DENND4A
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human DENND4A.
MW	209kDa
Properties
Concentration	1mg/ml
purification	By utilizing SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	Ensure that the product is stored at -20 °C for a period of one year to maintain its quality. It is important to avoid subjecting it to multiple freeze/thaw cycles.
Storage buffer	This product contains Rabbit IgG in phosphate buffered saline at a pH of 7.4, with 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at a temperature of -20 °C and has a shelf life of 12 months from the date of receipt. The content can be easily rearranged while still preserving the original information.
Target
Background	Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.
Tissue specificity	Expressed ubiquitously. Highest expression in bone marrow, medium in peripheral blood lymphocytes and lowest in spleen. In brain, breast, and prostate, higher expression was seen in normal cells than in tumor cells. Expression is regulated in a growth- and cell cycle-dependent manner.
Celluar localization	Cytosol;Nucleus;
UniPort	Q7Z401