Rabbit Anti-CXG2 Polyclonal Antibody#abs141157
Please note that the price mentioned above is for your reference only. For detailed pricing information, please reach out to our seller, Vecent. We advise you to directly contact Vecent to get accurate pricing details. This product is for research use only, not for use in diagnostic prodecures...
Description
| Catalog-specification | Delivery time | USD price |
abs141157-100ug | 1-2 Weeks | 301.0 |
abs141157-50ug | 1-2 Weeks | 201.0 |
Please note that the price mentioned above is for your reference only. For detailed pricing information, please reach out to our seller, Vecent. We advise you to directly contact Vecent to get accurate pricing details.
| Overview | |
catalog | abs141157 |
| Other names | Connexin 46.6, also known as connexin 47, is a gap junction protein that plays an important role in the communication between cells. It is encoded by the B230382L12Rik gene in mice and is highly conserved in humans as well, where it is also known as CXG2_HUMAN. This protein is involved in the formation of gap junctions, which are channels that allow small molecules and ions to pass between cells and facilitate various cellular processes. Connexin 46.6 is a member of the connexin family of proteins and is closely related to connexin 47. These proteins are both gamma-type connexins and play similar roles in the formation of gap junctions in various tissues. They are also similar in terms of their molecular weight, with gap junction protein alpha 12 47kDa and gap junction protein gamma 2 47kDa being two of the protein's aliases. Overall, connexin 46.6 is an essential component of gap junctions and is involved in the regulation of cell signaling, proliferation, and differentiation. Its expression has been found in a variety of tissues, including the brain, liver, and pancreas, and mutations in its encoding gene have been associated with certain hereditary diseases, such as spastic paraplegia type 44 and lymphedema. |
| Source | Rabbit |
| Specificity | The total levels of endogenous CXG2 can be detected using the CXG2 Antibody. One can rearrange the above content to generate a highly similar output. |
| Species Reactivity | Human |
| Antigen | CXG2 |
| Application | WB 1:500~1:1000，IF/ICC 1:100-1:500，ELISA(peptide) 1:20000-1:40000。，，。 |
| Immunogen | A synthesized peptide. |
| MW | 47 KD |
| Properties | |
Concentration | 1mg/ml |
| purification | Using SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. The resulting product was highly purified and ready for use in various applications. This method of purification is highly effective at isolating specific peptides and proteins from complex mixtures, ensuring the purity and specificity of the final product. Overall, the use of peptide affinity chromatography has allowed for the generation of a high-quality antiserum with excellent performance characteristics. |
| Clonality | Polyclonal Antibody |
| Stability & Storage | One should avoid repeated freeze/thaw cycles and store it at -20°C for a year. It is important to note that the storage guidelines should be strictly followed to maintain product quality. Maintaining the necessary storage conditions can help preserve the efficacy and integrity of the product. Therefore, it's advisable to adhere to the recommended storage temperatures to ensure optimal stability. |
| Storage buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. |
Target | |
Background | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems. |
| Tissue specificity | Expressed in central nervous system, in sciatic nerve and sural nerve. Also detected in skeletal muscles. |
| Celluar localization | Plasma Membrane; |
| UniPort | Q5T442 |
This product is for research use only, not for use in diagnostic prodecures or in human.
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