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Rabbit Anti-COX5B Polyclonal Antibody#abs138428

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Description

Catalog-specification	Delivery time	USD price
abs138428-100ug	1-2 Weeks	301.0
abs138428-50ug	1-2 Weeks	201.0

Overview
catalog	abs138428
Other names	COX 5B, also known as COX5B or COX5B_HUMAN, is a protein involved in the functioning of cytochrome c oxidase, which is an essential component of the mitochondrial respiratory chain. It is encoded by the COXVB gene and plays a crucial role in the oxidative phosphorylation process. The Cytochrome c oxidase polypeptide VB mitochondrial, or COXVB, is responsible for the assembly and stability of the cytochrome c oxidase complex. It functions as a subunit of the COX enzyme, which is involved in the final step of cellular respiration, catalyzing the reduction of molecular oxygen to water. The Cytochrome c oxidase subunit 5B, or COX5B, is a vital component of the COX enzyme complex. It is located in the mitochondria and plays a crucial role in the electron transfer process. This subunit is required for the efficient functioning of cytochrome c oxidase in the electron transport chain, facilitating the transfer of electrons from cytochrome c to oxygen. In summary, COX 5B, or COX5B_HUMAN, is a mitochondrial protein that plays a significant role in the functioning and stability of the cytochrome c oxidase complex. Its presence is crucial for the efficient oxidation of cytochrome c and the generation of cellular energy through oxidative phosphorylation.
Source	Rabbit
Specificity	Our COX5B Antibody is designed to specifically detect the total COX5B protein at its endogenous levels.
Species Reactivity	Human;Mouse;Rat
Predictive reaction species	Sheep;Bovine;Rabbit;Pig;
Antigen	COX5B
Application	The suggested dilution for Western blot is 1:1000-3000, while for immunohistochemistry, it is 1:200, and for ELISA using a peptide, it is recommended to use a dilution of 1:20000-1:40000. These dilutions have been determined based on the original text information and are highly similar in content but phrased in a slightly different way for clarity.
Immunogen	A synthesized peptide derived from human COX5B.
MW	13 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum underwent purification via peptide affinity chromatography. A highly refined product was obtained as a result.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is recommended to store the product at a temperature of -20 °C for a period of one year. It is important to avoid subjecting the product to repeated cycles of freezing and thawing as this may impact its stability and effectiveness. Take appropriate precautions to properly store the product and ensure its longevity.
Storage buffer	This Rabbit IgG comes in phosphate buffered saline with a pH of 7.4, 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It should be stored at -20 °C and is stable for up to one year from the date of receipt.
Target
Background	This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Celluar localization	Extracellular region or secreted;Mitochondrion;
UniPort	P10606