Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-Collagen IX Alpha2 Polyclonal Antibody#abs138425

Please note that the price stated above is only for your reference. For detailed pricing information, we kindly ask that you reach out to our seller, Vecent. Thank you. Western blot analysis Collagen IX α2 using COS7 whole cell lysates This product is for research use only, not for use in...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs138425-100ug	1-2 Weeks	301.0
abs138425-50ug	1-2 Weeks	201.0

Please note that the price stated above is only for your reference. For detailed pricing information, we kindly ask that you reach out to our seller, Vecent. Thank you.

Overview
catalog	abs138425
Source	Rabbit
Specificity	The Collagen IX α2 Antibody has the ability to detect the total levels of endogenous Collagen IX α2. This means that it is able to accurately identify and measure the amount of this particular collagen present within a sample. This is an important tool for researchers and medical professionals who need to understand the role that Collagen IX α2 plays in various biological processes. By being able to measure the levels of this protein, they can gain valuable insights into these processes, which could lead to improved treatments for related diseases and conditions.
Species Reactivity	Human;Mouse
Predictive reaction species	Pig;Xenopus;Rabbit;Sheep;Bovine;Horse;
Antigen	Collagen IX alpha2
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A peptide that has been synthesized from the alpha-2 chain of human Collagen IX is currently available. The structure of this peptide is highly similar to the natural protein, and it has been designed to mimic a specific region of the collagen molecule. This synthetic peptide may have applications in a variety of biomedical research areas, and it may also be used for therapeutic purposes. Researchers are currently exploring the potential uses of this peptide and investigating its various properties to better understand its potential applications.
MW	65 kDa
Properties
Concentration	1mg/ml
purification	Using SulfoLink™ Coupling Resin, the antiserum was subjected to peptide affinity chromatography in order to purify it.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure optimal storage conditions, it is recommended to keep the product at a temperature of -20 °C for a period of one year. It is important to note that you should avoid subjecting the product to repeated freeze/thaw cycles, as this can compromise the quality of the product. By following these guidelines, you can help to maintain the integrity of the product and ensure that it remains stable and effective over time.
Storage buffer	The storage conditions for Rabbit IgG are as follows: it should be stored at -20 °C in phosphate buffered saline with a pH of 7.4, containing 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is important to note that it is stable for 12 months from the date of receipt.
Target
Background	The structural component of the vitreous of the eye and hyaline cartilage plays a crucial role in maintaining their integrity and function. Both tissues contain a common component that contributes to their structural stability. This component, known as hyaluronic acid, is a key molecule found in abundance within both the vitreous of the eye and hyaline cartilage. Hyaline cartilage, as its name suggests, has a glassy appearance due to the high concentration of collagen fibers within its extracellular matrix. These fibers provide strength and support to the cartilage, allowing it to withstand mechanical stress and maintain its shape. In addition to collagen, hyaluronic acid is an essential structural component of hyaline cartilage. It binds to proteoglycans, which are large proteins that are embedded within the extracellular matrix. This association between hyaluronic acid and proteoglycans helps to form a hydrated gel-like substance that provides cushioning and shock absorption properties to the cartilage. Similarly, the vitreous of the eye also contains a high concentration of hyaluronic acid. This clear, gel-like substance fills the posterior segment of the eye, providing support to its internal structures. Hyaluronic acid in the vitreous plays a critical role in maintaining the shape of the eye, acting as a scaffold for other components such as collagen fibrils and proteoglycans. It helps to distribute nutrients and maintain necessary hydration levels within the vitreous, ensuring optimal functioning of the eye. In summary, hyaline cartilage and the vitreous of the eye both contain hyaluronic acid as a structural component. This molecule contributes to the integrity and function of these tissues by providing support, cushioning, and maintaining their shape. Understanding the importance of this common component can help in the development of treatments and interventions for conditions affecting these tissues.
Posttranslational modification	Covalently linked to the telopeptides of type II collagen by lysine-derived cross-links.Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
Celluar localization	Endoplasmic reticulum;Extracellular region or secreted;
UniPort	Q14055