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Rabbit Anti-CEP68 Polyclonal Antibody#abs138884

Description

Catalog-specification	Delivery time	USD price
abs138884-100ug	1-2 Weeks	301.0
abs138884-50ug	1-2 Weeks	201.0

Please note that the price mentioned above is just for your reference and not its actual price. Kindly reach out to our seller Vecent for more details on pricing. It's important to note that the content generated should be a highly similar version, but with different phrasing and structure to ensure that it's unique from the original text information. Let's make sure to use language modeling to generate content that is distinct from what was used in the ChapGPT model.

Overview
catalog	abs138884
Other names	Protein 68kDa Centrosomal; 68 kDa Centrosomal Protein; Cep68; CEP68_HUMAN; FLJ25920; FLJ36750; KIAA0582. Generating a variant content by reorganizing the provided information, I can say that Centrosomal Protein 68kDa, also known as Cep68, is a protein found within the centrosome. Its molecular weight is approximately 68 kilodaltons. It is encoded by the FLJ25920 gene, alternatively called FLJ36750 or KIAA0582.
Source	Rabbit
Specificity	Total CEP68 levels can be accurately detected using the CEP68 Antibody, which is capable of recognizing endogenous amounts of the protein. Let's create a completely distinct version of the content using a language model, rather than generating content through a conversation-based approach.
Species Reactivity	Human
Antigen	CEP68
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human CEP68.
MW	81 kDa
Properties
Concentration	1mg/ml
purification	SulfoLink™ Coupling Resin was utilized in the purification process of the antiserum through peptide affinity chromatography.
Clonality	Polyclonal Antibody
Stability & Storage	To ensure the longevity of the product, it is recommended to store it at a temperature of -20°C for a period of one year. It is important to note that repeated freeze/thaw cycles should be avoided in order to maintain the integrity of the product.
Storage buffer	The storage condition for Rabbit IgG is as follows: it should be stored at -20 °C in phosphate buffered saline with a pH of 7.4. The solution should contain 150mM NaCl, 0.02% sodium azide, and 50% glycerol. It is advised to store it in this manner for up to 12 months from the date of receipt.
Target
Background	This gene plays a crucial role in maintaining the cohesion of the centrosome by forming a linker structure that prevents its splitting. According to research studies, the protein product is also involved in the transport of CDK5RAP2 to the centrosome during the interphase of the cell cycle. The significance of this gene product is evident in various cellular processes, including mitosis and cell division. This information highlights the importance of the gene and its potential implications in various pathological conditions.
Posttranslational modification	Phosphorylation by PLK1 is required for binding to BTRC in prometaphase (PubMed:25503564). Phosphorylated directly or indirectly by NEK2 (PubMed:24554434). NEK2-mediated phosphorylation promotes CEP68 dissociation from the centrosome and its degradation at the onset of mitosis (PubMed:25704143).Ubiquitinated and targeted for proteasomal degradation in early mitosis by the SCF(BTRC) and/or SCF(FBXW11) E3 ubiquitin-protein ligase complexes (PubMed:25704143, PubMed:25503564). Degradation is complete by prometaphase and is required for removal of CDK5RAP2 from the peripheral pericentriolar material and subsequent centriole separation (PubMed:25503564).
Celluar localization	Cytoskeleton;Cytosol;Nucleus;
UniPort	Q76N32