Home - Products - Antibodies - Primary Antibodies - Polyclonal Antibody - Details

Rabbit Anti-CDYL1 Polyclonal Antibody#abs139608

Please note that the price mentioned above is only for your reference, for detailed pricing information, please get in touch with our sales representative Vecent. It is important to understand that the generated content should be based on the original text information but should be presented...

Send Inquiry

Description

Catalog-specification	Delivery time	USD price
abs139608-100ug	1-2 Weeks	301.0
abs139608-50ug	1-2 Weeks	201.0

Overview
catalog	abs139608
Other names	The CDY-like gene, also known as CDYL or chromodomain protein Y-like, is an autosomal gene that encodes for a protein similar to the Y chromosome-related protein. The CDYL protein contains a chromodomain motif that binds to histones and regulates chromatin function. Additionally, CDYL has been found to be specifically expressed in testis and may have a role in spermatogenesis. Recently, CDYL has been identified as a potential therapeutic target for cancer treatment. However, further research is needed to fully understand the functions and mechanisms of this gene and its protein product.
Source	Rabbit
Specificity	The detection of endogenous levels of total CDYL1 is possible using the CDYL1 Antibody. To ensure accurate results, it is important to use this antibody specifically designed for CDYL1 detection. It allows researchers to observe the natural levels of CDYL1 and study its functions in various biological processes.
Species Reactivity	Human
Predictive reaction species	Xenopus;Chicken;Pig;Dog;Sheep;Bovine;Horse
Antigen	CDYL1
Application	WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
Immunogen	A synthesized peptide derived from human CDYL1.
MW	66 kDa
Properties
Concentration	1mg/ml
purification	Utilizing SulfoLink™ Coupling Resin, the antiserum underwent purification through peptide affinity chromatography. To ensure the highest quality and purity, this process was carefully executed.
Clonality	Polyclonal Antibody
Stability & Storage	To preserve the product's quality for a year, it is important to store it at a temperature of -20 °C. It is crucial to avoid subjecting it to repeated freeze/thaw cycles.
Storage buffer	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.
Target
Background	Acts as a RE1-silencing transcription factor (REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4.
Tissue specificity	Ubiquitous. Expressed at moderate levels in all tissues examined. Isoform 2 is the most abundantly expressed isoform.
Celluar localization	Nucleus;
UniPort	Q9Y232